Campbell Biology in Focus
Campbell Biology in Focus
3rd Edition
ISBN: 9780134710679
Author: Lisa A. Urry, Michael L. Cain, Steven A. Wasserman, Peter V. Minorsky, Rebecca Orr
Publisher: PEARSON
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Chapter 10.1, Problem 1CC

MAKE CONNECTIONS Using what you know of gene expression in a cell, explain what causes traits of parents (such as hair color) to show up in their offspring. (See Concept 3.6 1)

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Think Critically. Provide a concise explanation of your answer. A mutation on an autosome causes a particular protein to be overproduced, and the excess protein accumulates in the liver and damages it. Would the resulting disorder most likely be inherited in an autosomal dominant or recessive pattern? Expression of the SYR gene on the Y chromosome gives rise to the male phenotype in humans. What do you think the inheritance pattern of SYR alleles is called? 22q11.2 deletion syndrome, also called DiGeorge syndrome, causes atypical parathyroid glands, a heart defect, and an underdeveloped thymus gland. About 85% of patients have a microdeletion of part of chromosome 22. A girl, her mother, and a maternal aunt have very mild DiGeorge syndrome. They all have a reciprocal translocation of chromosomes 22 and 2. How can a microdeletion and a translocation cause the same symptoms? Why were the people with the translocation less severely affected than the people with microdeletion? What other…
MAKE CONNECTIONS In a research article aboutalkaptonuria published in 1902, Garrod suggested thathumans inherit two “characters” (alleles) for a particularenzyme and that both parents must contribute a faultyversion for the offspring to have alkaptonuria. Today,would this disorder be called dominant or recessive?(See Concept 14.4.)
ou now have an understanding of Genomes, DNA Replication, Transcription, Translation, and Regulation of Genes. How would you reprogram skin cells to create cells which look and behave like brain cells (neurons)?  What would you change/modify to reprogram a skin cell to a neuron? How would you introduce the change/modification into the skin cells to transform them into neurons?
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QCE Biology: Introduction to Gene Expression; Author: Atomi;https://www.youtube.com/watch?v=a7hydUtCIJk;License: Standard YouTube License, CC-BY