Pearson eText Human Physiology: An Integrated Approach -- Instant Access (Pearson+)
8th Edition
ISBN: 9780135212905
Author: Dee Silverthorn
Publisher: PEARSON+
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Chapter 10.4, Problem 17CC
Summary Introduction
To determine: The reasons why does K+ rather than Na+ enter hair cells when their cation channels open.
Introduction: Sodium channels are voltage-gated channels that open against a specific electrical response. Neurons can be hyperpolarized or depolarize on the movement of different ions inside and outside of the cell. Depolarisation of the cell is mainly caused by the influx of sodium ions in the cell. Potassium ions help the cell membrane potential to reach resting membrane potential.
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The apical surfaces of hair cells are exposed to an unusual extracellular fluid called endolymph. Endolymph is relatively similar in ionic
composition to cytoplasm:
Select one:
O
O
a. it is high in Na+ (-150 mM), low in K+
b. It is high in K+ (250 mM), low in Na+
c. it is high in K+ (150 mM), low in Na+
d. It is high in Ca 2+ (-250 mM), low in Na+
(-2 mM), and relatively low in Ca 2+ (100 μM).
(-4 mM), and relatively low in Ca 2+ (150 µm).
(2 mM), and relatively low in Ca 2+ (100 µm).
(2 mM), and relatively low in K+ (150 M).
What happens to the membrane potential inside and outside of the cell when K+ channels are open?
What happens to Na+ when a neuron is stimulated on its dendrite? Why does the movement of Na+ raise the voltage on the plasma membrane?
Chapter 10 Solutions
Pearson eText Human Physiology: An Integrated Approach -- Instant Access (Pearson+)
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- What happens to the membrane potential inside and outside of the cell when Ca+ channels are open?arrow_forwardWhat characteristic of the basilar membrane is important for the function of the mechanically regulated gated K+ channelsof the hair cells? How do you think this characteristic changes as a person ages?arrow_forwardRead the following statements (a) The resting nerve membrane is freely permeable to Na*, K* ions and negatively charged proteins. (b) The activity of Na* - K* pump is responsible for maintaining resting membrane potential. (c) The resting membrane is impermeable to negatively charged proteins present in the axoplasm. Choose the option representing correct statements. b only a and b b and c a, b and carrow_forward
- If extracellular [Na1] is elevated, how would the resting potential and action potential of a neuron change?arrow_forwardWhat happens to the membrane potential inside and outside of the cell when Na+ channels are open?arrow_forwardThe concentration of potassium ions inside a nerve cell membrane is higher than the concentration of sodium ions outside the mem-brane, yet the inside of the membrane (where the cation concentra-tion is higher) is negative to the outside. Explain this observation in terms of permeability properties of the membrane.arrow_forward
- Help mearrow_forward1) The olfactory receptor neurons in frogs resemble those of mammals, in that they express olfactory receptors that are coupled to a G protein. When the G protein is activated, it activates an adenylyl cyclase to produce cAMP, which then opens cyclic-AMP gated cation channels in the plasma membrane. The opening of these channels depolarizes the membrane, leading to the production of an action potential. Your friend is interested in why neurons stop responding to an odor after prolonged exposure to it, a process called adaptation. He has conducted experiments examining the depolarization of the olfactory receptor neuron, the binding of odorant to the receptor, the activation of the G protein, the levels of CAMP in the cell, and the phosphorylation of adenylyl cyclase. His results are summarized in Table 1. depolarization of neuron? odorant binding to receptor? activation of the G protein? CAMP levels in the cell? adenylyl cyclase phosphorylation? no odor no no no low no Table 1 brief…arrow_forwardPhotoreceptor cells form glutamatergic synapses onto bipolar cells and when photoreceptor cells are depolarized the release of glutamate into the synapse is increased. One class of bipolar cells, (called OFF bipolar cells) have excitatory glutamate receptors in their post-synaptic specialization. What happens to the membrane potential of OFF bipolar cells when photoreceptors are illuminated?arrow_forward
- Consider the following three diagrams of a nerve cell membrane. They show resting potential, depolarization, and hyperpolarization. Figure out which one is which, then draw them in the order they occur in a cell that undergoes an action potential outside + Na* inside K* Na* Nat K Nat K Na potential: -80 mV outside + Na K* Na* inside Na+ K Nat Na* K+ potential: +30 mV outside Na Na Na Na* K+ inside K* Na* Kt potential: -70 mVarrow_forwardIn an experiment, the extracellular [Na+] surrounding a nerve cell was reduced from 145 to 45 mM. Which of the following is the most likely effect of this on action potentials? No action potentials would occur because the concentration of extracellular Na+ is too low. The membrane potential would become more negative so the threshold for action potential generation could not be reached. The nerve cell would still produce an action potential but its amplitude would be reduced and the depolarisation phase would be slower. The nerve cell would still produce an action potential but its amplitude would be reduced and the depolarization phase would be more rapid.arrow_forwardA drug that blocks Na+ channels in neurons does so not only in the axon but also in the dendrites and cell body. What overall effect would this have on action potential generation?arrow_forward
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