Bio 121 Campbell Biology Truman College
Bio 121 Campbell Biology Truman College
17th Edition
ISBN: 9781323670637
Author: Urry, Cain
Publisher: PEARSON
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Chapter 11, Problem 7TYU

Protein phosphorylation is commonly involved with all of the following except

  • (A) activation of receptor tyrosine kinases.
  • (B) activation of protein kinase moleculcs.
  • (C) activation of G protein-coupled receptors.
  • (D) regulation of transcription by signaling molecules.
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1) Amino acids that contain hydroxyl groups in their R-groups can be phosphorylated during cellular signaling. (a) What amino acids can be phosphorylated? (use the one letter amino acid abbreviations) (b) Does phosphorylation turn a signaling protein “on” or “off”? (c) Whatis the most common source of a phosphate used to phosphorylate a protein (d) What enzyme type (or category of enzymes)removes phosphates from proteins?
Signaling by tyrosine kinase receptors is generally associated with all of the following except: A) receptor dimerization B) growth factor responses C) heterotrimeric G proteins D) cross phosphorylation E) generating protein binding sites due to phosphorylation
Cellular signaling follows a cascade of events and has multiple points of regulation. Which of the following could be a reason(s) why a signalling cascade is interrupted, or turned 'off', once it has been turned 'on'? A) a protein gets tagged with an ubiqutin group and gets degraded B) a chemical modification occurred on serine, threonine, or tyrosine side chains to turn on/off proteins C) allosteric regulation causes an active site to be hidden D) All of the other answers are correct E) The ligand is prevented from reaching the binding site

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Bio 121 Campbell Biology Truman College

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