Fundamentals of Biostatistics
8th Edition
ISBN: 9781305268920
Author: Bernard Rosner
Publisher: Cengage Learning
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Chapter 11, Problem 95P
Diabetes
A group of 10-year-old boys were first ascertained in a camp for diabetic boys. They had their weight measured at baseline and again when they returned to camp 1 year later. Each time, a serum sample was obtained from which a determination of hemoglobin Ale (HgbAlc) was made. HgbAlc (also called glycosylated hemoglobin) is routinely used to monitor compliance with taking insulin injections. Usually, the poorer the compliance, the higher the HgbA1 c level will be. The hypothesis is that the level HgbAlc is related to weight. The data in Table 11.28 were obtained.
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TABLE 11.28 Relationship between weight change and change In HgbAlc among diabetic boys
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Chapter 11 Solutions
Fundamentals of Biostatistics
Ch. 11.12 - What is the difference between an ordinary...Ch. 11 - Hematology The data in Table 11.17 are given for 9...Ch. 11 - Hematology The data in Table 11.17 are given for 9...Ch. 11 - Hematology The data in Table 11.17 are given for 9...Ch. 11 - Prob. 4PCh. 11 - Prob. 5PCh. 11 - Prob. 6PCh. 11 - Hematology The data in Table 11.17 are given for 9...Ch. 11 - Prob. 8PCh. 11 - Pulmonary Function Suppose the correlation...
Ch. 11 - Prob. 10PCh. 11 - Prob. 11PCh. 11 - Prob. 12PCh. 11 - Hypertension The Update to the Task Force Report...Ch. 11 - Prob. 14PCh. 11 - Prob. 31PCh. 11 - Prob. 32PCh. 11 - Prob. 49PCh. 11 - Refer to Data Set BONEDEN.DAT at www.cengagebrain...Ch. 11 - Prob. 92PCh. 11 - Prob. 93PCh. 11 - Prob. 94PCh. 11 - Diabetes A group of 10-year-old boys were first...Ch. 11 - Prob. 118PCh. 11 - Prob. 119PCh. 11 - Prob. 120PCh. 11 - Prob. 121P
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- Population Genetics In the study of population genetics, an important measure of inbreeding is the proportion of homozygous genotypesthat is, instances in which the two alleles carried at a particular site on an individuals chromosomes are both the same. For population in which blood-related individual mate, them is a higher than expected frequency of homozygous individuals. Examples of such populations include endangered or rare species, selectively bred breeds, and isolated populations. in general. the frequency of homozygous children from mating of blood-related parents is greater than that for children from unrelated parents Measured over a large number of generations, the proportion of heterozygous genotypesthat is, nonhomozygous genotypeschanges by a constant factor 1 from generation to generation. The factor 1 is a number between 0 and 1. If 1=0.75, for example then the proportion of heterozygous individuals in the population decreases by 25 in each generation In this case, after 10 generations, the proportion of heterozygous individuals in the population decreases by 94.37, since 0.7510=0.0563, or 5.63. In other words, 94.37 of the population is homozygous. For specific types of matings, the proportion of heterozygous genotypes can be related to that of previous generations and is found from an equation. For mating between siblings 1 can be determined as the largest value of for which 2=12+14. This equation comes from carefully accounting for the genotypes for the present generation the 2 term in terms of those previous two generations represented by for the parents generation and by the constant term of the grandparents generation. a Find both solutions to the quadratic equation above and identify which is 1 use a horizontal span of 1 to 1 in this exercise and the following exercise. b After 5 generations, what proportion of the population will be homozygous? c After 20 generations, what proportion of the population will be homozygous?arrow_forwardUrban Travel Times Population of cities and driving times are related, as shown in the accompanying table, which shows the 1960 population N, in thousands, for several cities, together with the average time T, in minutes, sent by residents driving to work. City Population N Driving time T Los Angeles 6489 16.8 Pittsburgh 1804 12.6 Washington 1808 14.3 Hutchinson 38 6.1 Nashville 347 10.8 Tallahassee 48 7.3 An analysis of these data, along with data from 17 other cities in the United States and Canada, led to a power model of average driving time as a function of population. a Construct a power model of driving time in minutes as a function of population measured in thousands b Is average driving time in Pittsburgh more or less than would be expected from its population? c If you wish to move to a smaller city to reduce your average driving time to work by 25, how much smaller should the city be?arrow_forward
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