Campbell Biology
Campbell Biology
12th Edition
ISBN: 9780135188743
Author: Urry
Publisher: PEARSON
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Chapter 11.2, Problem 1CC
Summary Introduction

To know: The location of NGF receptor in cell.

Introduction: Nerve growth factor (NGF) is a molecule, which helps to regulate growth and development and it also maintains the sensory neurons. The nerve growth factor (NGF) is involved in the growth and survival of neurons.

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Nerve growth factor (NGF) is a water-soluble signalingmolecule. Would you expect the receptor for NGF to beintracellular or in the plasma membrane? Why?
Suppose that a G protein undergoes a mutation that allows the exchange of bound GTP for GDP to occur in the absence of G protein binding to a receptor. How might this mutation affect signaling involving a GPCR? Which subunit of the G protein is most likely affected by the mutation?
What type of cell signaling receptor is depicted below   a. Cytoplasmic Receptor   b. Transmembrane Receptor   c. Intracellular Receptor   d. Nuclear Receptor

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