FUND.OF ANAT.+PHYS.(LOOSE)-PACKAGE
12th Edition
ISBN: 9780134862057
Author: Martini
Publisher: PEARSON
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Chapter 12, Problem 23RQ
Summary Introduction
To explain:
The number of the excitatory neurons that must be stimulated to produce an action potential if all the five neuroinhibitory neurons are stimulated.
Concept introduction:
The action potential of the neuron is +30mV. The resting membrane potential is -70mV. The difference between the action potential and the resting membrane potential is 100mV. The minimum of ten neurons are required to maintain the action potential in the presence of five inhibitory potential.
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Consider the neuron below, which has a membrane resting potential of -70mV, membrane space constant of
Imm, membrane time constant of 100ms, and spike firing threshold of -65mV. The neuron receives input from
three synapses. Synapse A generates an EPSP of 12mV amplitude and 2ms duration, synapse B generates an
EPSP of 8mV amplitude and Ims duration, and synapse C generates an IPSP with an amplitude of -2mV and
duration of 3ms.
A
axon hillock
0.5mm
Justify your answers to the following questions mathematically (round distances to nearest 0.5mm). You can
neglect propagation time (ie. assume EPSPS/IPSPS arrive at axon hillock at same time irrespective of distance).
(a) Would the cell fire an action potential if A is active?
(b) Would the cell fire an action potential if A and B are active simultaneously?
(c) Would the cell fire an action potential if B is activated twice with a delay of 2ms?
(d) Would the cell fire an action potential if all three are simultaneously active?
(e) If an…
If a postsynaptic cell has synapses from five different cells, and three cause EPSPs and two of them cause IPSPs, give an example of a series of depolarizations and hyperpolarizations that would result in the neuron reaching threshold.
A neuron has a resting membrane potential of -70 milivolts (mV) and a threshold value of -55 mV. Three synapses on the body of this neuron receive the
impulses listed below.
hyperpolarisation by 5 mV
• depolarisation by 15 mV
• depolarisation by 10 mV
ENTER THE MEMBRANE POTENTIAL AS A NUMBER WITH + OR - IN FRONT OF IT.
The final membrane potential will be
mV and this
cause an action potential becasue it is
v than the
Chapter 12 Solutions
FUND.OF ANAT.+PHYS.(LOOSE)-PACKAGE
Ch. 12 - Describe the three anatomical divisions of the...Ch. 12 - Describe the two functional divisions of the...Ch. 12 - Identify the two components of the efferent...Ch. 12 - Prob. 4CPCh. 12 - Name the structural components of a typical...Ch. 12 - Classify neurons according to their structure.Ch. 12 - Classify neurons according to their function.Ch. 12 - Prob. 8CPCh. 12 - Prob. 9CPCh. 12 - Prob. 10CP
Ch. 12 - Prob. 11CPCh. 12 - Prob. 12CPCh. 12 - Prob. 13CPCh. 12 - What effect would decreasing the concentration of...Ch. 12 - Define action potential.Ch. 12 - Identify the steps involved in the generation and...Ch. 12 - Prob. 17CPCh. 12 - Which of the following axons is myelinated: one...Ch. 12 - Prob. 19CPCh. 12 - Prob. 20CPCh. 12 - What effect would blocking voltage-gated calcium...Ch. 12 - Prob. 22CPCh. 12 - Prob. 23CPCh. 12 - Prob. 24CPCh. 12 - Prob. 25CPCh. 12 - Prob. 26CPCh. 12 - Prob. 27CPCh. 12 - LEVEL 1 Reviewing Facts and Terms 1. Label the...Ch. 12 - Prob. 2RQCh. 12 - Prob. 3RQCh. 12 - Prob. 4RQCh. 12 - The neural cells responsible for the analysis of...Ch. 12 - Depolarization of a neuron plasma membrane will...Ch. 12 - Prob. 7RQCh. 12 - Receptors that bind acetylcholine at the...Ch. 12 - What are the major components of (a) the central...Ch. 12 - Prob. 10RQCh. 12 - Prob. 11RQCh. 12 - If the resting membrane potential of a neuron is...Ch. 12 - Prob. 13RQCh. 12 - What is the difference between anterograde flow...Ch. 12 - What is the functional difference among chemically...Ch. 12 - State the all-or-none principle cf action...Ch. 12 - Prob. 17RQCh. 12 - Prob. 18RQCh. 12 - What are the structural and functional differences...Ch. 12 - Describe the events that occur during nerve...Ch. 12 - Prob. 21RQCh. 12 - Prob. 22RQCh. 12 - Prob. 23RQCh. 12 - In multiple sclerosis, there is intermittent and...Ch. 12 - Prob. 25RQCh. 12 - Which cells of the CNS are targeted by the polio...Ch. 12 - Prob. 2CC
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