Fundamentals of Anatomy & Physiology, Modified MasteringA&P with eText and Access Card (10th Edition)
10th Edition
ISBN: 9780133988550
Author: Frederic H. Martini, Judi L. Nath, Edwin F. Bartholomew
Publisher: PEARSON
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Chapter 12, Problem 25CP
Summary Introduction
To determine:
Whether the action potential will be generated or not, if one EPSP depolarizes the initial segment from a resting membrane potential of -70 mV to -65 mV, considering threshold to be -60 mV.
Introduction:
Postsynaptic potential refers to graded potential that develops in the membrane of a postsynaptic cell. This can be of two types, excitatory postsynaptic potential (EPSP) and inhibitory postsynaptic potential (IPSP).
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At the peak of an action potential, would the relative permeability of Na be higher than K? Which ion would be the least permeable to the membrane during falling phase?
Describe the contribution of each of the following to the establishment and maintenance of membrane potential:
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Resting membrane potential is approximately -70mV. Explain what resting membrane potential is and what -70mV refers to.
What is the expected resting membrane potential (in mV) of a neuron that is typical in all ways except for possessing an intracellular potassium concentration of 94 mM and double the normal resting permeability to sodium?
Chapter 12 Solutions
Fundamentals of Anatomy & Physiology, Modified MasteringA&P with eText and Access Card (10th Edition)
Ch. 12 - Prob. 1CPCh. 12 - Describe the two functional divisions of the...Ch. 12 - 3. Identify the two components of the efferent...Ch. 12 - Prob. 4CPCh. 12 - Name the structural components of a typical...Ch. 12 - Classify neurons according to their structure.Ch. 12 - Classify neurons according to their function.Ch. 12 - Prob. 8CPCh. 12 - Prob. 9CPCh. 12 - Prob. 10CP
Ch. 12 - Prob. 11CPCh. 12 - Prob. 12CPCh. 12 - Prob. 13CPCh. 12 - What effect would decreasing the concentration of...Ch. 12 - Define action potential.Ch. 12 - Identify the steps involved in the generation and...Ch. 12 - Prob. 17CPCh. 12 - Which of the following axons is myelinated: one...Ch. 12 - Prob. 19CPCh. 12 - Prob. 20CPCh. 12 - What effect would blocking voltage-gated calcium...Ch. 12 - Prob. 22CPCh. 12 - Prob. 23CPCh. 12 - Prob. 24CPCh. 12 - Prob. 25CPCh. 12 - Prob. 26CPCh. 12 - Prob. 27CPCh. 12 - LEVEL 1 Reviewing Facts and Terms 1. Label the...Ch. 12 - Prob. 2RQCh. 12 - Prob. 3RQCh. 12 - Prob. 4RQCh. 12 - The neural cells responsible for the analysis of...Ch. 12 - Depolarization of a neuron plasma membrane will...Ch. 12 - Prob. 7RQCh. 12 - Receptors that bind acetylcholine at the...Ch. 12 - What are the major components of (a) the central...Ch. 12 - Prob. 10RQCh. 12 - Prob. 11RQCh. 12 - If the resting membrane potential of a neuron is...Ch. 12 - Prob. 13RQCh. 12 - What is the difference between anterograde flow...Ch. 12 - What is the functional difference among chemically...Ch. 12 - State the all-or-none principle cf action...Ch. 12 - Prob. 17RQCh. 12 - Prob. 18RQCh. 12 - What are the structural and functional differences...Ch. 12 - Describe the events that occur during nerve...Ch. 12 - Prob. 21RQCh. 12 - Prob. 22RQCh. 12 - Prob. 23RQCh. 12 - In multiple sclerosis, there is intermittent and...Ch. 12 - Prob. 25RQCh. 12 - Prob. 1CCCh. 12 - Prob. 2CC
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- Describe the action potential in terms of the different functional states of the voltage- gated Na+ membrane channels (Note: there are three states)arrow_forwardWhat is the expected resting membrane potential (in mV) of a neuron that is typical in all ways except for possessing an extracellular potassium concentration of 104.3 mM, an intracellular sodium concentration of 103.6 mM, and 4 times the normal resting permeability to sodium?arrow_forwardDraw details of the repolarization phase of an action potential from the following descriptions of the sequences of AfterHyperPolarization (AHP) and AfterDePolarization (ADP) sequences. Make the distinct phases clear and noticeable (5 % each) A complex AHP consisting of a first component AHP, an ADP, and a second component AHP before repolarization to resting membrane potential a first fast AHP component, followed by a slower AHP, followed by a fast ADP, and a second late AHP component before repolarization to restarrow_forward
- Compare the resting membrane potential of a neuron with the potassium and sodium equilibrium potentials. Explain how this comparison relates to the relative permeabilities of the resting plasma membrane to these two ions.arrow_forwardThe resting membrane potential of a neuron typically is 70 mV. What does this mean?arrow_forwardAt the peak of the neuronal action potential, Vm is approximately +50 mV. Assuming normal intracellular and extracellular K+ concentrations ( [K+]o = 4 mM, [K+]i = 150 mM ), what is the driving force (in mV) that acts on K+ ions at the peak of the action potential?arrow_forward
- In the figure to the left, name the 4 phases of the action potential (Note: you have to write in where phase 4 occurs). Describe what happens in each phase with a focus on Na+ and K+ flow through channels and the membrane potential. Discuss the importance of threshold. How does this relate to the concept of APs being all or none?arrow_forwardAt the peak of the action potential, Vm is approximately -65 mV. Assuming normal intracellular and extracellular K+ concentrations (refer to the table), (1) calculate the driving force (in mV) that acts on K+ ions and (2) use the information obtained in part 1 to determine the direction in which K+ ions will flow (i.e., into the cell or out of cell)arrow_forwardDescribe the contribution of each of the following to the establishment and maintenance of membrane potential: Part A Na+K+ Pump Passive movement of K+ across the membrane Passive movement of Na+ across the membranearrow_forward
- What kind of graded potential describes a change in membrane potential from 70 to 60 mV? From 70 to 80 mV?arrow_forwardWhat is the difference between a resting membranepotential and an action potential?arrow_forwardWhat is the equilibrium membrane potential due to Na+ ions if the extracellular concentration of Na+ ions is 154 mM and the intracellular concentration of Na+ ions is 23 mM at 20 ∘C ?arrow_forward
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