EBK BIOLOGY
6th Edition
ISBN: 9780134819150
Author: Maier
Publisher: VST
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Chapter 12, Problem 4LTB
Summary Introduction
Antibiotics are the drugs that kill microbes including bacteria. Antibiotics are effective in controlling infections through their immune system.
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Drug-resistant TB can be acquired via sequential mutations in the pathogen’s genome, or via transmission of a resistant pathogen from another person. How can these events be distinguished? Why is it important to know which is more prevalent?
Different strains of Streptococcus pyogenes have different virulence factors, giving these microbes much versatility. Virulence factors include which of the following? Choose one or more:
A.A capsule that, when thick, will help the organism avoid phagocytosis by macrophages
B.A cell wall containing lipoteichoic acid, thought to facilitate adherence to pharyngeal epithelial cells
C.Enzymes that lyse blood cells (streptolysins)
D.The production of several endotoxins called streptococcal pyogenic endotoxins (SPEs)
Using the Koch's Postulates, support the findings
that Mycobacterium tuberculosis is the causative
agent of tuberculosis. Specifically, you have to
provide brief narratives/pictures/proofs and
sources that support the postulate listed below:
The organism must be isolated from the newly
infected animals and cultured again in the
laboratory, after which it should be seen to be
the same as the original organism.
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- What cells inside our bodies would be affected if you ingested a suspension of T4 phage? Describe and explain the difference in results if Staphylococcus aureus were used instead of Escherichia coli.arrow_forwardAlthough Lilly's project was focused on understanding the prevalence of resistance strains of M. tuberculosis in indigenous populations, she also knew that many patients infected with TB do not have an active disease, ie that the bacteria is latent in the infected lungs. M. tuberculosis is transmitted indirectly via air droplets that are inhaled in the large and small airways. In fact, although 30% of individuals exposed to the bacteria will develop an infection, only 5-10% will develop clinical manifestations. This means 20-25% of people exposed to the bacteria will have a latent disease. Although people with latent disease are not infectious and will not transmit the disease to other community members, latent disease is difficult to diagnose. This was really playing on Lilly's mind, thinking about the difficulty of controlling the spread of the bacteria when most infected people were asymptomatic for years and then suddenly developed active disease, which could then spread for weeks…arrow_forwardDiscuss why it is important for us to conduct research at the basic level of physiology in order to better understand what makes Mycobacteria latent or grow during an infection so that we can design new and/or better treatment modalities.arrow_forward
- Which infection would be easier to contract from eating seafood, shigellosis or cholera? Explain. Give typing answer with explanation and conclusionarrow_forwardcan you explain why Bacillus anthracis can be pathogenic in a mouse and not be fought off by the immune system? I need help finding the answer in the article and explain in short answer link to article: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC106848/arrow_forwardShow the process of Mycobacterium tuberculosis in a diagram.arrow_forward
- Below are a list of virulence factors/ strategies paired with an example of an organism that utilizes them. How do each of the following strategies contribute to the virulence of the pathogen? Strategy - Causes the host to produce more receptors (Organism - Rhinovirus) Strategy - Produces gas as a product of fermentation (Organism - Clostridium perfringens) Strategy - Produces a capsule (organism - Klebsiella pneumonia) Strategy - Ability to move between adjacent cells (organism - Cytomegalovirus) Strategy - Ability to use pilus as a motility structure (organism - Pseudomonas aerogenosa)arrow_forwardCytomegalovirus has the ability to move between adjacent cells: How does Cytomagalovirus contribute to the virulence of the pathogen?arrow_forwardHow does Mycobacterium tuberculosis gain access through that preferred portal of entry Explain how the Mycobacterium tuberculosis is able to evade innate human host defenses that prevent this from occurring. discuss specific components of your pathogen. (Examples may include capsules, cell wall components, exoenzymes, antigenic variation and penetration of the host cell cytoskeleton.)arrow_forward
- Which of the following highly contagious viruses is a single-stranded ribonucleic acid (RNA) virus with a helical capsid and envelope and is transmitted by coming in contact with respiratory secretions? "This is a highly contagious respiratory illness transmitted when an infected person coughs or sneezes virus particles into the air," the health department said in a written statement. "It's so contagious that if one person is sick and spreading measles, nine out of 10 people around them who aren't immune will get it, too." Group of answer choices a. Measles b. Parvovirus c. Coxsackie virus A d. Rhinovirusarrow_forwardDoes Mycobacterium tuberculosis produce an exotoxin or endotoxin Discuss how this affects the host. This is where most of the damage is caused.explain the difference between an EXOTOXIN and an ENDOTOXIN.arrow_forwardAs part of your job in an international pharmaceutical company you are given the task of: a) Developing a cheaper method for the production of vitamin C b) Developing a live cholera vaccine Describe how you would accomplish these tasksarrow_forward
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