Campbell Biology
12th Edition
ISBN: 9780135188743
Author: Urry
Publisher: PEARSON
expand_more
expand_more
format_list_bulleted
Concept explainers
Videos
Textbook Question
Chapter 12, Problem 4TYU
The decline of MPF activity at the end of mitosis is due to
(A) the destruction of the protein kinase Cdk.
(B) decreased synthesis of Cdk.
(C) the degradation of cyclin.
(D) the accumulation of cyclin.
Expert Solution & Answer
Want to see the full answer?
Check out a sample textbook solution
Students have asked these similar questions
Vinblastine is a standard chemotherapeutic drug used to treatcancer. Because it interferes with the assembly of microtubules,its effectiveness must be related to(A) disruption of mitotic spindle formation.(B) suppression of cyclin production.(C) myosin denaturation and inhibition of cleavage furrowformation.(D) inhibition of DNA synthesis.
Which of the following events does not take place during mitosis?(a) The centromeres of the chromosomes split. (b) The nucleoli disappear, and the two centrosomes separate from one another. (c) The nuclear envelope breaks. (d) Four daughter cells are generated. (e) The chromosomes cluster at the cell’s equator.
(a) the cell cycle is divided into different phases (referred to as M, G0, G1, S and G2); Can you account for what happens during the different parts of the cycle and out of it is checked? ( b) What is the difference between apoptosis and necrosis? ( c) What are caspases and what is their function in the cell?
Chapter 12 Solutions
Campbell Biology
Ch. 12.1 - How many chromosomes are drawn in each part of...Ch. 12.1 - WHAT IF? A chicken has 78 chromosomes in its...Ch. 12.2 - How many chromosomes are shown in the illustration...Ch. 12.2 - Compare cytokinesis in animal cells and plant...Ch. 12.2 - During which stages of the cell cycle does a...Ch. 12.2 - Compare the roles of tubulin and actin during...Ch. 12.2 - A kinetochore has been compared to a coupling...Ch. 12.2 - MAKE CONNECTIONS What other functions do actin...Ch. 12.3 - In Figure 12.14, why do the nuclei resulting from...Ch. 12.3 - How does MPF allow a cell to pass the G2 phase...
Ch. 12.3 - MAKE CONNECTIONS Explain how receptor tyrosine...Ch. 12 - Differentiate between these terms: chromosome,...Ch. 12 - In which of the three phases of interphase and the...Ch. 12 - Explain the significance of the G1, G2, and M...Ch. 12 - Through a microscope, you can see a cell plate...Ch. 12 - Vinblastine is a standard chemotherapeutic drug...Ch. 12 - One difference between cancer cells and normal...Ch. 12 - The decline of MPF activity at the end of mitosis...Ch. 12 - In the cells of some organisms, mitosis occurs...Ch. 12 - Which of the following does not occur during...Ch. 12 - Cell A has half as much DNA as cells B, C, and D...Ch. 12 - The drug cytochalasin B blocks the function of...Ch. 12 - VISUAL SKILLS The light micrograph shows dividing...Ch. 12 - DRAW IT Draw one eukaryotic chromosome as it would...Ch. 12 - EVOLUTION CONNECTION The result of mitosis is that...Ch. 12 - SCIENTIFIC INQUIRY Although both ends of a...Ch. 12 - WRITE ABOUT A THEME: INFORMATION The continuity of...Ch. 12 - SYNTHESIZE YOUR KNOWLEDGE For selected answers,...
Additional Science Textbook Solutions
Find more solutions based on key concepts
A student moving out of a dormitory crouches in correct fashion to lift a heavy box of books. What prime movers...
HUMAN ANATOMY
Which of the following would be used to identify an unknown bacterial culture that came from a patient in the i...
Microbiology Fundamentals: A Clinical Approach
6. How can you use the features found in each chapter?
Human Anatomy & Physiology
How does trandlation differ from transcription?
Microbiology: Principles and Explorations
2. Why is it that the range of resting blood pressures of humans is best represented by a bell-shaped curve co...
Human Biology: Concepts and Current Issues (8th Edition)
Some people consider Pasteur or Koch to be the Father of Microbiology, rather than Leeuwenhoek. Why might they ...
Microbiology with Diseases by Body System (4th Edition)
Knowledge Booster
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- . 2 3 1 4 . 5 6 I 7. .. (a) Identify the point in mitosis at which separase cleaves the protein complex that holds sister chromatid pairs together. In normal cells, separase is kept in an inactive state until it is needed. Explain how the progression of cells past sequential cell cycle checkpoints and the activity of enzymes such as separase is controlled by interactions between two major groups of regulatory proteins. (b) Identify an independent variable in the experiment graphed in Figure 1. Based on the data in Figure 1, identify a control that shows that Sepin-1 rather than something else in the culture medium is inhibiting the growth of the cancer cells. (c) Based on the data in Table 1, describe the general relationship between the sensitivity of cells to Sepin-1 and the concentration of separase in the cells. Use the Figure 1 data to calculate the ratio between the amount of Sepin-1 required to kill 50% of the cells in the cell line that is most sensitive to the compound and the…arrow_forwardAmount of DNA per nucleus over the cell division cycle. At which point in the accompanying figure does MPF reach its highest activity during the cell division cycle? a) I b) II c) III d) IVarrow_forwardA hypothetical poison prevents transcription factors from binding to the gene for tubulin proteins. What impact would this have on mitosis, and why?arrow_forward
- What experimental evidence indicates that cyclin B is re-quired for a cell to enter mitosis? What evidence indicates that cyclin B must be destroyed for a cell to exit mitosis?arrow_forwardMatch the process with the correct phase of the cell cycle (G1, S, G2, M). If the process occurs in M phase indicate subphase (ex. telophase). A) ___________________ The bipolar spindle forms from microtubules. B) ___________________ The nucleus breaks down. C) ___________________ Mitochondria are duplicated. D) ___________________Sister chromatids are formed. E) ___________________Extra cell membrane is synthesized by the smooth ER. F) ___________________DNA is compacted into chromatin.arrow_forwardDuring an experimental study, an investigator finds that the regulation of cell cycle and programmed cell death may be initiated by the mitochondrion. The interaction of the mitochondrion with the activation of the caspase family of proteases and subsequent apoptosis is most likely mediated by which of the following? (A) Calcium release (B) cAMP production (C) Cytochrome c release (D) GTP binding (E) Nitric oxide releasearrow_forward
- Some cancer drugs stop cell division by stabilizing microtubules so they cannot come apart. Which step of the mitosis is disrupted? A) Telophase B) cytokinesis C) Anaphase D) Metaphasearrow_forward1. (a) Describe the generalized model of the cell cycle. Demonstrate how cyclins and cyclin-dependent kinases can regulate the cell cycle. (b). Describe three ways in which cells lose their ability to regulate their growth to become cancerous.arrow_forward(46) A mutated form of protein pox is found in patients with squamous cell carcinoma. In vitro studies show that the normal p5x molecule binds to DNA, and neoplastic cells accumulate in the G0 phase of the cell cycle. In contrast, the mutated form of p5x does not bind to DNA. These finding are most characteristics of which of the following? (A) Growht factor receptors (B) GTP-binding protein (C) Nonreceptor tyrosine kinases (D) Oncogene proteins (E) Tumor suppressor gene proteinsarrow_forward
- Biopsies from aggressive cancers often have cells that contain several nuclei per cell when viewed through a microscope. Which scenario could explain how such a multinucleated cell might have come to be? (a) The cell underwent repeated mitosis with simultaneous cytokinesis. (b) The cell had multiple S phases before it entered mitosis. (c) The cell underwent repeated mitosis, but cytokinesis did not occur. (d) The cell underwent repeated cytokinesis but no mitosis. (e) The cell actually went through meiosis and not mitosis.arrow_forwardWhich of the following is true with respect to cyclins and CDKs? A) CDKs promote progression of the cell cycle, cyclins function to inhibit progression of the cell cycle B) CDKs are the checkpoints in the cell cycle, and when bound to cyclins, they stop progression of the cell cycle C) CDKs will only work to promote progression of the cell cycle when complexed with their designated cyclins D) CDKs are rarely expressed during a cell's cycle, unless cyclins are present to act as transcription factors .arrow_forward(46) A mutated form of protein p5x is found in patients with squamous cell carcinoma. In vitro studies show that the normal p5x molecule binds to DNA, and neoplastic cells accumulate in the G0 phase of the cell cycle. In contrast, the mutated form of p5x does not bin d to DNA. These finding are most characteristics of which of the following? (A) Growht factor receptors (B) GTP-binding protein (C) Nonreceptor tyrosine kinases (D) Oncogene proteins (E) Tumor suppressor gene proteinsarrow_forward
arrow_back_ios
SEE MORE QUESTIONS
arrow_forward_ios
Recommended textbooks for you
Human Anatomy & Physiology (11th Edition)BiologyISBN:9780134580999Author:Elaine N. Marieb, Katja N. HoehnPublisher:PEARSON
Biology 2eBiologyISBN:9781947172517Author:Matthew Douglas, Jung Choi, Mary Ann ClarkPublisher:OpenStax
Anatomy & PhysiologyBiologyISBN:9781259398629Author:McKinley, Michael P., O'loughlin, Valerie Dean, Bidle, Theresa StouterPublisher:Mcgraw Hill Education,
Molecular Biology of the Cell (Sixth Edition)BiologyISBN:9780815344322Author:Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter WalterPublisher:W. W. Norton & Company
Laboratory Manual For Human Anatomy & PhysiologyBiologyISBN:9781260159363Author:Martin, Terry R., Prentice-craver, CynthiaPublisher:McGraw-Hill Publishing Co.
Inquiry Into Life (16th Edition)BiologyISBN:9781260231700Author:Sylvia S. Mader, Michael WindelspechtPublisher:McGraw Hill Education
Human Anatomy & Physiology (11th Edition)
Biology
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:PEARSON
Biology 2e
Biology
ISBN:9781947172517
Author:Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher:OpenStax
Anatomy & Physiology
Biology
ISBN:9781259398629
Author:McKinley, Michael P., O'loughlin, Valerie Dean, Bidle, Theresa Stouter
Publisher:Mcgraw Hill Education,
Molecular Biology of the Cell (Sixth Edition)
Biology
ISBN:9780815344322
Author:Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter Walter
Publisher:W. W. Norton & Company
Laboratory Manual For Human Anatomy & Physiology
Biology
ISBN:9781260159363
Author:Martin, Terry R., Prentice-craver, Cynthia
Publisher:McGraw-Hill Publishing Co.
Inquiry Into Life (16th Edition)
Biology
ISBN:9781260231700
Author:Sylvia S. Mader, Michael Windelspecht
Publisher:McGraw Hill Education
The Cell Cycle and its Regulation; Author: Professor Dave Explains;https://www.youtube.com/watch?v=eqJqhA8HSJ0;License: Standard YouTube License, CC-BY
Cell Division - Mitosis and Meiosis - GCSE Biology (9-1); Author: Mr Exham Biology;https://www.youtube.com/watch?v=w7vp_uRA8kw;License: Standard YouTube License, CC-BY