The drug cytochalasin B blocks the function of actin. Which of the following aspects of the animal cell cycle would be most disrupted by cytochalasin B?
(A) spindle formation
(B) spindle attachment to kinetochores
(C) cell elongation during anaphase
(D) cleavage furrow formation and cytokinesis
Want to see the full answer?
Check out a sample textbook solutionChapter 12 Solutions
Mastering Biology with Pearson eText - Standalone Access Card - for Campbell Biology (11th Edition)
Additional Science Textbook Solutions
Fundamentals of Anatomy & Physiology Plus Mastering A&P with eText - Access Card Package (10th Edition) (New A&P Titles by Ric Martini and Judi Nath)
Laboratory Experiments in Microbiology (11th Edition)
Concepts of Biology
Campbell Biology: Concepts & Connections (9th Edition)
Human Biology: Concepts and Current Issues (8th Edition)
Study Guide for Campbell Biology
- What is a chromosome? How many chromosomes are in humans? 2.- What are the phases of the cell cycle? Why are important? 3.- a: What is the interphase ? b: Please explain the phases of the interphase. 4.- Why the cells are capable to maintain the homeostasis? 5.- Please name the organelles in the cell, and explain Golgi Apparatus, and Nucleolus: __________________.arrow_forwardOne important biological effect of a large dose of ionizing radiation (like X-rays) is to halt cell division. How does this occur? To answer this question, state the name and role of 2 specific and important proteins involved in the process. What happens if a cell has a mutation that prevents it from halting cell division after be irradiated? Be specific and detailed. An adult human who has reached maturity will die within a few days of receiving a radiation dose large enough to stop cell division. What does that tell you about cell division? In addition, name 2 different/unique cell types that would be primarily affected.arrow_forwardName the two overarching phases of the cell cycle? How long does the complete cell cycle take in mammalian cells in culture ?arrow_forward
- Attachment of the mitotic spindle fibers to the kinetochores is a characteristic of which stage of mitosis? a. prophase b. prometaphase c. metaphase d. anaphasearrow_forwardWhat are the three types of microtubules involved in the formation of the mitotic spindle? Briefly describe the contribution of each to successful cell division.arrow_forwardMitotic spindle function relies heavily on microtubule motors. For each of the following motor proteins, predict the effect on spindle formation, function, or both of adding a drug that specifically inhibits only that motor: kinesin-5, kinesin-13, and kinesin-4.arrow_forward
- Between which two stages of the Neurospora life cycle do most mitotic cell divisions occur?arrow_forwardWhich of the following statements is FALSE? A. Centrosomes are anchor points for microtubules and are essential to form the mitotic spindle. B. In the eukaryotic cell cycle the cell spends much more time in the interphase than in the mitotic phase. C. In telophase two nuclear envelopes are fully formed and the cell splits in two via cytokinesis. D. The contraction of the kinetochore microtubules leads to the separation of the sister chromatids during anaphase. E. In the prophase chromatin condenses into X-shaped chromosomes.arrow_forwardWhat experimental evidence indicates that cyclin B is re-quired for a cell to enter mitosis? What evidence indicates that cyclin B must be destroyed for a cell to exit mitosis?arrow_forward
- Speculate about the following details of mitosis. 1. Why do chromosomes need to condense during mitosis? 2. Why does the nuclear membrane need to break down at the beginning of prometaphase? 3. Why do chromosomes congress (migrate) toward the metaphase plate during metaphase, and what forces keep the chromosomes there until anaphase begins? 4. What would happen if one kinetochore of one chromosome failed to attach to the spindle and the cell entered anaphase? In a general sense, how do cells normally prevent this situation? 5. During late anaphase and telophase, animal cells elongate to aid the eventual separation of the two daughter cells in cytokinesis. This elongation can occur even in cell suspensions, where different cells do not come into contact. Are the forces that elongate the cell likely to be pushing forces or pulling forces, and where do these forces come from?arrow_forwardNewly forming astral microtubules associate with dynein motor proteins, with the tail of the dynein bound to the plasma membrane. This association appears to be important in the distribution of astral microtubules to the polar regions (opposite “ends”) during spindle assembly.Now fast forward to the events of anaphase. In which phase of Anaphase (A or B) does the association between astral microtubules and membrane-bound dynein play a role? What is that role? (Your answer should incorporate information on how the directionality of dynein’s movement is involved in the process you describe.)arrow_forwardScientists in a lab have isolated a substance that prevents cells from synthesizing spindle fibres. How would this substance affect cell division? Explain.arrow_forward
- Biology (MindTap Course List)BiologyISBN:9781337392938Author:Eldra Solomon, Charles Martin, Diana W. Martin, Linda R. BergPublisher:Cengage Learning