Chemistry in Context
Chemistry in Context
8th Edition
ISBN: 9780073522975
Author: American Chemical Society
Publisher: McGraw-Hill Education
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Chapter 12.5, Problem 12.14CT

Scientific Practices Function Follows Form

In sickle cell anemia, a glutamic acid residue in the sequence of hemoglobin is replaced with a valine residue.

Chapter 12.5, Problem 12.14CT, Scientific Practices Function Follows Form In sickle cell anemia, a glutamic acid residue in the

  1. a. Describe the structural difference between these two amino acids: valine and glutamic acid.
  2. b. Predict the solubility for each of these amino acids in water.
  3. c. Explain how these differences could give rise to the deformed cells typified by sickle cell anemia.
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