To determine The lung compliance of an individual when given that at the end of normal expiration, the lung volume is 2L, the alveolar pressure is 0mmHg and the intrapleural pressure is -4mmHg, and at the end of normal inspiration the lung volume is 800mL, the alveolar pressure is 0mmHg and the intrapleural pressure is -8mmHg.
Introduction: Lung compliance is the magnitude of change in lung volume generated through a change in the transpulmonary pressure (Ptp). It can be calculated using the formula give below:
Where, CL represents lung compliance, ∆V represents change in volume, ∆Ptp represents change in transpulmonary pressure, Palv represents alveolar pressure and Pip represents intrapleural pressure.
Transpulmonary pressure is the difference between the alveolar pressure and the intrapleural pressure. It can be calculated as:
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Vander's Human Physiology
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