Biological Science (7th Edition)
Biological Science (7th Edition)
7th Edition
ISBN: 9780134678320
Author: Scott Freeman, Kim Quillin, Lizabeth Allison, Michael Black, Greg Podgorski, Emily Taylor, Jeff Carmichael
Publisher: PEARSON
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Chapter 15, Problem 3TYK

How are Okazaki fragments synthesized?

a. using the leading strand template, and synthesizing 5' → 3'

b. using the leading strand template, and synthesizing 3' → 5'

c. using the lagging strand template, and synthesizing 5'→ 3'

d. using the lagging strand template, and synthesizing 3'→ 5'

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Compare and contrast how the lagging strand is replicated in E. coli and in eukaryotes. Highlight the steps that are the same or similar, as well as the aspects of lagging strand synthesis that differ.
A mutant DNA strand was transcribed then translated to proteins. a. What is the protein product of the mutant DNA strand? The sequence of the mutant strand is shown below: 5'-TGCCATAACTGTTCGTACTGGCAAATTGCC-3' 3'-ACGGTATTGACAAGCATGACCGTTTAACGG-5' b. The mutation altered the sequence of the wild type template DNA such that a degenerate codon for a basic amino acid in the wild type was converted to a non-degenerate codon resulting in the sequence for the mutant strand shown. What was the original amino acid? c. Compare the charges and pl of the mutant peptide and the normal (wild- type) peptide at physiological pH?
Strand directed mismatch repair corrects copying erros based on which ones apply to sentence above?  a. the strand containg breaks in the sugar backbone of the replicated DNA  b. structurral instabilities created between oncorrect base pairing and associated histone proteins c. mutations that are evolutionary beneficial to an organims and recults in these areas of the genetic code to be turned off d. methylation of adenosine in GATC sequences during bacterial DNA replication e. repair sequence motifs that attract DNA polymerase gamma
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