Microbiology: An Introduction
11th Edition
ISBN: 9780321733603
Author: Gerard J. Tortora, Berdell R. Funke, Christine L. Case
Publisher: Benjamin Cummings
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Chapter 15, Problem 5R
Summary Introduction
To review:
The similarities and differences between endotoxins and exotoxins on the following aspects: bacterial source, chemistry, toxicity, and pharmacology.
Introduction:
Microorganisms that have the ability to cause infectious diseases are called as pathogens. Such microorganisms include bacteria,
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Compare endotoxins and exotoxins produced by bacteria to include: 1) the type(s) or source(s) of bacteria that produce each toxin2) what each toxin is composed of3) how each toxin is released into the environment
Which of the following is true of selective toxicity?
O 1) It refers to the process of determining the correct dose of a particular drug
O 2) To be effective, an antimicrobial agent must be more toxic to the patient than
2)
the pathogen
O 3) It contributes to antibiotic resistance
O 4) It refers to the body's ability to protect the brain and eye
5)
It takes advantage of metabolic and structural differences between host and
pathogen
Identify the structural features, origins, and majoreffects of endotoxins.
Chapter 15 Solutions
Microbiology: An Introduction
Ch. 15 - Compare pathogenicity with virulence.Ch. 15 - How are capsules and cell wall components related...Ch. 15 - Prob. 3RCh. 15 - Explain how drugs that bind each of the following...Ch. 15 - Prob. 5RCh. 15 - Prob. 6RCh. 15 - Prob. 7RCh. 15 - Which of the following genera is the most...Ch. 15 - How can viruses and protozoa avoid being killed by...Ch. 15 - Prob. 10R
Ch. 15 - Prob. 1ACh. 15 - Prob. 2ACh. 15 - Prob. 3ACh. 15 - How do each of the following strategies contribute...Ch. 15 - The removal of plasmids reduces virulence in which...Ch. 15 - Prob. 2MCQCh. 15 - Prob. 3MCQCh. 15 - All of the following can occur during bacterial...Ch. 15 - The ID50 for Campylobacter sp. is 500 cells; the...Ch. 15 - Prob. 6MCQCh. 15 - A drug that binds to mannose on human cells would...Ch. 15 - The earliest smallpox vaccines were infected...Ch. 15 - Prob. 9MCQCh. 15 - Which of the following statements is true? a. The...Ch. 15 - On July 8, a woman was given an antibiotic for...Ch. 15 - Explain whether each of the following examples is...Ch. 15 - Cancer patients undergoing chemotherapy are...
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- Describe the differences in bacterial endotoxin and bacterial exotoxins with respect to mode of action, signs and symptoms, and body’s response to these toxins. What would you say is the logical reason bacteria make toxins?arrow_forwardCompare and contrast Bacterial Endotoxins and Exotoxins at 4 levels:arrow_forwardHere are four toxins: diphtheria toxin, cholera toxin, tetanus toxin, and exfoliative toxin. Choose two of them and answer the following questions: 1. Is it an exotoxin or an endotoxin? 2. Which bacterial species produces it? 3. Briefly describe its mode of action and how it causes damage to the host cells. Include specific signs and symptoms.arrow_forward
- (b) List TWO (2) types of common food hazards. Describe the properties of bacteria endotoxin based on the following component; (i) (ii) (iii) Stability Antigenicity Toxicityarrow_forwardWhat are two reasons microbes will produce toxins?arrow_forwardChoose one infectious disease from the list below and use the chain of infection to analyze how it is spread. A. Please provide a comprehensive description of cholera. B. Describe the chain of infection cholera. The chain of infection for the chosen infectious disease must clearly include the following: 1. Identification of a) the pathogen, b) the reservoir c) means of transmission d) the susceptible host 2. Describe how one could break the chain of cholera, such as breaking the pathogen link, by providing a specific intervention. 3. Include references and relevant data.arrow_forward
- Describe in detail the exotoxin and endotoxin with examples and diagrams. note: please write as much as you can, the more the betterarrow_forwardEndotoxin is associated witha) Gram-positive bacteria.b) Gram-negative bacteria.c) the cytoplasmic membrane.d) endospores.arrow_forwardDefine the term pathogen. Using MRSA, NOROVIRUS, ATHLETES FOOT and MALARIA as examples, identify the microorganisms (causal agent) involved in each disease. Provide some information on the microorganism for each disease e.g. structure Discuss 3 routes of entry that disease causing organisms use to enter the body.arrow_forward
- Which of the following is NOT true of bacterial exotoxins? 1. Important in the pathogenesis of many human diseases 2. Their toxic effect can be systemic, affecting cells distant from the primary site of infection 3. None of the other four answers (All are true of bacterial exotoxins) 4. Different exotoxins may affect different types of cells (e.g., nerves, gastrointestinal mucosa) 5. Some exotoxins have two components, A (active) and B (binding)arrow_forwardSelective toxicity of a drug refers to a) damage to pathogenic organisms only b) damage to prokaryotic cell membranes c) damage to the target organisms but not the host cell d) easily broken down by the host and pathogen.arrow_forwardDefine 43-kDa connexinarrow_forward
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