Foundations in Microbiology
9th Edition
ISBN: 9780073522609
Author: Kathleen Park Talaro, Barry Chess Instructor
Publisher: McGraw-Hill Education
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Question
Chapter 15.L2, Problem 1CT
Summary Introduction
To identify:
Reason for cells contain built in suicide genes to self destruct by apoptosis under certain conditions.
Introduction:
The apoptosis is genetically programmed and results in destruction of the nucleus and complete cell lysis and death.
Expert Solution & Answer
Explanation of Solution
- Virally infected cells - Cytotoxic cells recognize and react against other cells that carry virus peptide MHC combinations expressed on their surface. Cytotoxic defenses are an essential protection against viral infections.
- Cancer cells - T cells constantly survey the tissues and immediately attack any abnormal cells they encounter. The importance of this function is clearly demonstrated in the susceptibility of T-cell-deficient people to cancer.
- Cells from other animals and humans - Cytotoxic cell mediated immunity is the most important factor in graft rejection. In this instance, the TC cells attack the foreign tissues that have been implanted into a recipient’s body.
Conclusion
Hence, built in suicide genes is necessary to handle conditions, like graft rejection, cancer cells and virally infected cells.
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Chapter 15 Solutions
Foundations in Microbiology
Ch. 15.1 - Summarize the general features of adaptive,...Ch. 15.1 - Prob. 2ELOCh. 15.1 - Prob. 3ELOCh. 15.1 - Prob. 4ELOCh. 15.1 - Describe the major events in the origin of...Ch. 15.1 - Describe the development of antigen receptors on...Ch. 15.1 - Discuss what is meant by immunocompetence, immune...Ch. 15.1 - What function do receptors play in specific immune...Ch. 15.1 - Prob. 3CYPCh. 15.1 - Explain the clonal selection theory of receptor...
Ch. 15.1 - Why must the body develop tolerance to seit?Ch. 15.1 - Prob. 6CYPCh. 15.2 - Prob. 7ELOCh. 15.2 - Explain the characteristics of antigens, the...Ch. 15.2 - Discuss the main categories of antigens, based on...Ch. 15.2 - What is happening during lymphocyte maturation?Ch. 15.2 - Prob. 8CYPCh. 15.2 - What are antigens, immunogens, and epitopes, and...Ch. 15.2 - How do foreignness, size, and complexity...Ch. 15.2 - Compare five unique types of antigens, and explain...Ch. 15.3 - Describe the cooperative interactions between...Ch. 15.3 - Discuss the actions of interleukins in the early...Ch. 15.3 - Prob. 12ELOCh. 15.3 - Prob. 13ELOCh. 15.3 - Prob. 14ELOCh. 15.3 - Prob. 15ELOCh. 15.3 - Prob. 12CYPCh. 15.3 - Prob. 13CYPCh. 15.3 - Prob. 14CYPCh. 15.3 - Prob. 15CYPCh. 15.3 - Prob. 16CYPCh. 15.3 - What are the functions of plasma cells, clonal...Ch. 15.3 - Prob. 18CYPCh. 15.3 - Prob. 19CYPCh. 15.3 - Describe the attachment of antibodies to antigens....Ch. 15.3 - Prob. 21CYPCh. 15.3 - Prob. 22CYPCh. 15.3 - What causes the latent period and the anamnestic...Ch. 15.4 - Prob. 16ELOCh. 15.4 - Prob. 17ELOCh. 15.4 - Prob. 18ELOCh. 15.4 - Prob. 19ELOCh. 15.4 - Prob. 24CYPCh. 15.4 - Prob. 25CYPCh. 15.4 - What are the targets of cytotoxic cells and how do...Ch. 15.5 - Prob. 20ELOCh. 15.5 - Differentiate between natural and artificial...Ch. 15.5 - Expand on the four combinations of the defining...Ch. 15.5 - Prob. 27CYPCh. 15.5 - Name at least two major ways in which natural and...Ch. 15.5 - Prob. 29CYPCh. 15.6 - Explain the purposes of immunotherapy and...Ch. 15.6 - Describe the sources and uses of artificial...Ch. 15.6 - Discuss which factors are involved in vaccine...Ch. 15.6 - Identify the major categories of vaccine antigens,...Ch. 15.6 - Prob. 27ELOCh. 15.6 - Describe the preparation of killed vaccines; live,...Ch. 15.6 - Prob. 31CYPCh. 15.6 - Prob. 32CYPCh. 15.6 - Prob. 33CYPCh. 15.L1 - Which of these characteristics is not a major...Ch. 15.L1 - Prob. 2MCQCh. 15.L1 - In humans, B cells mature in the _____________ and...Ch. 15.L1 - Small, simple molecules are_________antigens. a....Ch. 15.L1 - Which type of cell actually secretes antibodies?...Ch. 15.L1 - CD4 cells are ________ cells and CD8 cells are...Ch. 15.L1 - Prob. 7MCQCh. 15.L1 - Prob. 8MCQCh. 15.L1 - Prob. 9MCQCh. 15.L1 - Prob. 10MCQCh. 15.L1 - Prob. 11MCQCh. 15.L1 - Prob. 12MCQCh. 15.L1 - Prob. 13MCQCh. 15.L1 - A living microbe with reduced virulence that is...Ch. 15.L1 - A vaccine that contains parts of viruses is called...Ch. 15.L1 - Prob. 16MCQCh. 15.L1 - Prob. 17MCQCh. 15.L1 - Prob. 18MCQCh. 15.L1 - Prob. 19MCQCh. 15.L1 - Prob. 20MCQCh. 15.L1 - Prob. 1CSRCh. 15.L1 - Prob. 2CSRCh. 15.L1 - Prob. 3CSRCh. 15.L1 - Using words and arrows, complete a flow outline of...Ch. 15.L1 - Prob. 2WCCh. 15.L1 - Prob. 3WCCh. 15.L1 - Prob. 4WCCh. 15.L1 - Prob. 5WCCh. 15.L1 - Prob. 6WCCh. 15.L2 - Prob. 1CTCh. 15.L2 - Prob. 2CTCh. 15.L2 - Double-stranded DNA is a large, complex molecule,...Ch. 15.L2 - Prob. 4CTCh. 15.L2 - Describe the relationship between an antitoxin, a...Ch. 15.L2 - Prob. 6CTCh. 15.L2 - Prob. 7CTCh. 15.L2 - Prob. 8CTCh. 15.L2 - Prob. 9CTCh. 15.L2 - Prob. 1VCCh. 15.L2 - Examine figure 6.6c and determine which components...
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