The Immune System, 4th Edition
4th Edition
ISBN: 9780815344667
Author: Peter Parham
Publisher: W. W. Norton & Company
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Question
Chapter 16, Problem 16Q
Summary Introduction
Case summary:
A patient, age 19 years reported with increased sweating, insomnia, palpitations and enlarged thyroid gland which upon investigation revealed an autoimmune disorder called Grave's disease.
Characters in the case:
Courtney Povlosky, the patient under evaluation.
Adequate information:
The patient's blood investigations show elevated T3 and T4 levels but lower than normal TSH levels compared to reference ranges. Further antibody tests confirmed the presence of anti-TSH receptor antibodies in her serum. She was treated with an antithyroid drug to which she responded well.
To Determine:
The reason why patients with Grave's disease have low TSH levels though their symptoms are that of hyperthyroidism.
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