Microbiology With Diseases.. -Masteringmic.
5th Edition
ISBN: 9780134298719
Author: BAUMAN
Publisher: PEARSON
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Textbook Question
Chapter 16, Problem 2VI
The nearby image is a transmission electron micrograph of a dendritic cell. Indicate where a scientist could find molecules of MHC I and MHC II. Label a pseudopod and a vesicle.
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Write T if the statement is correct; write F if the statement is not correct.
Antigen fragments that bind to MHC class I molecules are typically in endosomes. " "
TAP1 and TAP2 are present on the plasma membrane of APCs. " "
Proteasomes process antigens within the endoplasmic reticulum. " "
Newly synthesized MHC class I molecules can be found within endosomes. " "
Newly synthesized MHC class I α chains assemble in the ER with calnexin. " "
Match the appropriate term on the left with the appropriate definition of the right
Pathogen-Associated Molecular Pattern
MCH II
MHC I
Pattern Recognition Receptor
A.
A large macromolecule produced by pathogens which is unlike any macromolecule produced by the host
B.
An immune molecule which displays proteins from phagocytosed pathogens on the immune cell surface
C.
An immune molecule which displays normal cell proteins or proteins from intracellular pathogens on the surface of any host cell
D.
An immune receptor which recognizes macromolecules produced by broad classes of pathogens
how would you explain this article to someone to summarize the article and its sections?
https://www.frontiersin.org/articles/10.3389/fimmu.2017.00292/full
Major Histocompatibility Complex (MHC) Class I and MHC Class II Proteins: Conformational Plasticity in Antigen Presentation
Chapter 16 Solutions
Microbiology With Diseases.. -Masteringmic.
Ch. 16 - Prob. 1MCCh. 16 - Prob. 2MCCh. 16 - Prob. 3MCCh. 16 - Prob. 4MCCh. 16 - Prob. 5MCCh. 16 - Prob. 6MCCh. 16 - Prob. 7MCCh. 16 - Which cells express MHC class I molecules in a...Ch. 16 - Prob. 9MCCh. 16 - Prob. 10MC
Ch. 16 - Prob. 1TFCh. 16 - Prob. 2TFCh. 16 - Prob. 3TFCh. 16 - Prob. 4TFCh. 16 - Prob. 5TFCh. 16 - Prob. 1MCh. 16 - Prob. 2MCh. 16 - Prob. 1VICh. 16 - The nearby image is a transmission electron...Ch. 16 - Prob. 1SACh. 16 - Prob. 2SACh. 16 - Prob. 1CTCh. 16 - Contrast innate defenses with adaptive immunity.Ch. 16 - Prob. 3CTCh. 16 - Prob. 4CTCh. 16 - Prob. 5CTCh. 16 - Prob. 6CTCh. 16 - Prob. 7CTCh. 16 - Some materials, such as metal bone pins and...Ch. 16 - Prob. 9CTCh. 16 - Prob. 10CTCh. 16 - Prob. 11CTCh. 16 - Prob. 12CTCh. 16 - Prob. 13CTCh. 16 - Prob. 14CTCh. 16 - Prob. 1CMCh. 16 - Prob. 1TMWCh. 16 - Prob. 2TMWCh. 16 - Prob. 3TMWCh. 16 - Prob. 4TMWCh. 16 - Prob. 5TMWCh. 16 - Prob. 1EDCS
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- Which of the following statements pertain to this cell. This cell is a precursor to a cell which: 1. is an antigen-presenting cell 2. demonstrates MHC I molecules 3. demonstrates MHC II molecules 4. demonstrates CD4 molecules 5. is capable of synthesizing and releasing perforin and granzymes Choose from the following: (A) 1, 2, and 3 (B) 2 and 3 only (C) 3 and 4 only (D) 1 and 3 (E) 1, 4, and 5arrow_forwardWhich of the following is NOT true of B ceIls?a. Has membrane-bound antibodies.b. Produces antibodies when activated into plasma cells.c. Has MHC class II molecules.d. Kills infected body cells.arrow_forwardWhich of the following best describes the sequence variation within class | MHC molecules? A) Concentrated in the peptide-binding groove B) Concentrated near the transmembrane domain C) Concentrated within the cytoplasmic domain D) Concentrated within microglobulin E) Distributed fairly evenly throughout the moleculearrow_forward
- Can a mouse infected with Bacillus anthracis generate antibodies against the S-layer? How do you know? I need help finding the answer in the article and explain in short answer link to article: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC106848/arrow_forwardWrite T if the statement is correct; write F if the statement is not correct. Interferons enhance antigen presentation. " " Peptides that bind to MHC class II molecules are longer than those that bind MHC class I molecules. " " MHC molecules that lack a bound peptide is unstable. " " MHC class I:peptide:TCRcomplexes and MHC class II:peptide:TCR complex shows very similar orientation. " " The Golgi apparatus is part of the endomembrane system. " "arrow_forwardWhich of the following interactions will NOT provoke an immune response? A. Endogenous antigen + MHC Class I + TCR + CD 8+ B. Exogenous antigen + MHC Class II + TCR + CD 4+ C. Exogenous antigen + MHC Class II + BCR D. Endogenous antigen + MHC Class I + BCRarrow_forward
- Why Spleen(Mouce/mice) cells are used in the production of monoclonal antibodies? Why not other cells? Please answer at your own words.arrow_forwardMHC class II proteins: A. present exogenous antigen to the immune system B. both are found on antigen presenting cells and present exogenous C. antigen to the immune system are found on antigen presenting cellsarrow_forwardUse the following choices for the next set of questions. A choice may be used zero or more times: a)MHC class I b) MHC class Il C) both MHC class I and II d) neither MHC class | or II e) cannot be determined 21) expressed on T cells 22) captures antigens present in endosomes 23) strongly affected by proteasomal inhibition 24) downregulated by many viruses 25) the genes responsible for expression are monomorphic, meaning that identical alleles are shared throughout the populationarrow_forward
- Which of the following are TRUE of class I major histocompatibility complex (MHC) molecules? a. Class I MHC molecules present endogenous antigens. b. Class I MHC molecules are only present on erythrocyte surfaces. c. Class I MHC molecules bind complement. d. Class I MHC molecules present exogenous antigens.arrow_forwardType I, or immediate, hypersensitivity triggers plasma cells to secrete:- a. IgD b. IgM c. IgE d. IgAarrow_forwardAbout Antigen presenting cells, it is CORRECT to affirm that: a). Macrophages, B lymphocytes and dendritic cells are APCs. meaning they express MHC-ll. b). Only APCs present MHC-11. c). Macrophages,B lymphocytes and dendritic cells are phagocytes, but not APCs.d). All the non-APC cells of our body present MHC-1.arrow_forward
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