Essentials of Genetics
9th Edition
ISBN: 9781292108933
Author: KLUG
Publisher: PEARSON
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Chapter 16, Problem 3PDQ
What is the relationship between signal transduction and cellular proliferation?
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What is the relationship between signal transduction and cellularproliferation?
What is the main benefit of cell signaling via direct physical contact and cell signaling over short distances (ex: nerve cell signaling)?
Can a cell have multiple responses to one stimulus?
A) Yes, such as a second messenger activating a kinase and a transcription factor
B) No, one stimulus = one response.
C) Yes, but only if the stimulus activates two different types of receptors, like a GPCR and a protein kinase receptor at the same time
Chapter 16 Solutions
Essentials of Genetics
Ch. 16 -
CASE STUDY | I thought it was safe
A middle-aged...Ch. 16 -
CASE STUDY | I thought it was safe
A middle-aged...Ch. 16 -
CASE STUDY | I thought it was safe
A middle-aged...Ch. 16 - HOW DO WE KNOW? In this chapter, we focused on...Ch. 16 -
2. Review the Chapter Concepts list on page 307....Ch. 16 - What is the relationship between signal...Ch. 16 - Where are the major regulatory points in the cell...Ch. 16 -
5. Describe kinases and cyclins. How do they...Ch. 16 - (a) How does pRB function to keep cells at the G1...Ch. 16 - What is the difference between saying that cancer...
Ch. 16 -
8. What is apoptosis, and under what...Ch. 16 - Define tumor-suppressor genes. Why is a mutation...Ch. 16 - A genetic variant of the retinoblastoma protein,...Ch. 16 -
11. Part of the Ras protein is associated with...Ch. 16 - If a cell suffers damage to its DNA while in S...Ch. 16 - Prob. 13PDQCh. 16 - Prob. 14PDQCh. 16 - Prob. 15PDQCh. 16 - Prob. 16PDQCh. 16 - Prob. 17PDQCh. 16 - How do normal cells protect themselves from...Ch. 16 - Prob. 19PDQCh. 16 - Explain how environmental agents such as chemicals...Ch. 16 - Radiotherapy (treatment with ionizing radiation)...Ch. 16 - Genetic tests that detect mutations in the BRCA1...Ch. 16 - Prob. 23PDQCh. 16 - Prob. 24PDQCh. 16 - Prob. 25PDQCh. 16 - Prob. 26PDQCh. 16 - Prob. 27PDQCh. 16 - Prob. 28PDQ
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- Does Dpp stimulate cell division, cell growth, or both? How can you tell?arrow_forwardAs a cancer researcher, which segment of the signal transduction pathway would you target to prevent the spread of cancer and why?arrow_forwardWhat are the mechanisms governing stem cell division, self-renewal, and differentiation?arrow_forward
- A Patients with an inherited cancer have a mutation in a zinc-finger motif of P21 (a cell-cycle regulatory gene). Which of the following is the most likely result of this A) Decreased binding of a transcription factor to a DNA sequence B) Enhanced binding of hormones to receptors C) Enhanced transport of a hormone receptor complex into the nucleus D) Stimulation of mRNA synthesis E) "Unzipping" of leucine-rich helicesarrow_forwardWhat common features are shared by most cell signaling systems?arrow_forwardHow Do Mitochondria Mediate Apoptosis?arrow_forward
- What is the main benefit of cell signaling over long distances (ex: signaling via hormone secretion into the bloodstream)?arrow_forwardHow does a signal that binds to the surface of the cell reach all the way to the nucleus? is this about second massengerarrow_forwardWhat would happen if Stem Cells do not undergo Cell differentiation?arrow_forward
- What are the two major mechanisms through which cell signaling leads to a change in cell behavior?arrow_forwardWhat statement about Cdks/Cyclins below is false? A) Cyclins phosphorylate Cdks B) Cdks are kinases C) Cdk expression is constant during the cell cycle D) Cyclin expression fluctuates during the cell cycle E) Cdk activity fluctuates during the cell cyclearrow_forwardWhen some cancer cells produce growth factors that stimulate their own division leading to continuous self- stimulation for cell division it is referred to as a) TNF tumor necrosis factor b) AGS autocrine growth stimulationarrow_forward
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Intro to Cell Signaling; Author: Amoeba Sisters;https://www.youtube.com/watch?v=-dbRterutHY;License: Standard youtube license