Connect with LearnSmart Labs Access Card for Seeley's A&P
11th Edition
ISBN: 9781259807657
Author: Cinnamon VanPutte, Jennifer Regan, Andrew F. Russo Dr., Rod R. Seeley Dr.
Publisher: MCGRAW-HILL HIGHER EDUCATION
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Textbook Question
Chapter 17.4, Problem 17AYP
What characteristics ofa hormone receptor make itspecific for one type of hormone?
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What are the two classes of hormone receptors? How dothey differ in the chemical category of hormones that willbind to them? Give examples of the types of hormonesthat bind to each type of receptor
Suppose that the circulating concentration of hor-mone is 10–10 M and the Kd for binding to its receptor is 10–8M. What fraction of the receptors will have hormone bound?If a meaningful physiological response occurs when 50% ofthe receptors have bound a hormone molecule, how muchwill the concentration of hormone have to rise to elicit aresponse? The fraction of receptors (R) bound to hormone(H) to form a receptor–hormone complex (R–H) is [R–H]/([R] + [R–H]) = [R–H]/[R]TOT = [H]/([H] + Kd).
Hormone receptor molecules are the key to understanding specific-ity of hormone action on target cells. Describe and distinguish be-tween receptors located on the cell surface and those located in the nucleus of target cells. Name two hormones whose action is medi-ated through each type of receptor.
Chapter 17 Solutions
Connect with LearnSmart Labs Access Card for Seeley's A&P
Ch. 17.1 - Name and describe the four classes of chemical...Ch. 17.1 - Prob. 2AYPCh. 17.1 - In what ways does the nervous system differ from...Ch. 17.1 - How does an endocrine gland differ from an...Ch. 17.2 - Prob. 5AYPCh. 17.2 - Prob. 6AYPCh. 17.2 - Prob. 7AYPCh. 17.2 - What effect does a bound hormone have on the...Ch. 17.2 - What are the two chemical categories of hormones?...Ch. 17.2 - Describe how the chemical nature of a hormone...
Ch. 17.2 - Prob. 11AYPCh. 17.2 - Why do organs regulated by protein hormones have...Ch. 17.2 - Prob. 13AYPCh. 17.2 - Describe chronic, acute, and episodic patterns of...Ch. 17.3 - Describe and give examples of the three major ways...Ch. 17.3 - Prob. 16AYPCh. 17.4 - What characteristics ofa hormone receptor make...Ch. 17.4 - What is down-regulation, and what may cause it to...Ch. 17.4 - Prob. 19AYPCh. 17.4 - What are the two classes of hormone receptors? How...Ch. 17.4 - Prob. 21AYPCh. 17.4 - Prob. 22AYPCh. 17.4 - Prob. 23AYPCh. 17.4 - What two ways can a membrane-bound receptor use to...Ch. 17.4 - Explain how the hormone-receptor complex can alter...Ch. 17.4 - List four intracellular mediators affected by G...Ch. 17.4 - Prob. 27AYPCh. 17.4 - Prob. 28AYPCh. 17.4 - Prob. 29AYPCh. 17.4 - Prob. 30AYPCh. 17 - Prob. 1RACCh. 17 - Prob. 2RACCh. 17 - Which of these can regulate the secretion of a...Ch. 17 - Prob. 4RACCh. 17 - Prob. 5RACCh. 17 - Concerning the half-lifeof hormones, a....Ch. 17 - Prob. 7RACCh. 17 - Prob. 8RACCh. 17 - Prob. 9RACCh. 17 - Prob. 10RACCh. 17 - Prob. 11RACCh. 17 - Which of these can limit a cell's response to a...Ch. 17 - Prob. 13RACCh. 17 - Prob. 14RACCh. 17 - When a hormone binds to a nuclear receptor a. DNA...Ch. 17 - Prob. 16RACCh. 17 - Prob. 1CTCh. 17 - Prob. 2CTCh. 17 - Prob. 3CTCh. 17 - Prob. 4CTCh. 17 - Prob. 5CTCh. 17 - Prob. 6CTCh. 17 - Thyroid hormones are important in regulating the...Ch. 17 - Prob. 8CTCh. 17 - Prob. 9CT
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- Which statement correctly identifies how a lipid-soluble hormone that diffuses from the blood and through the interstitial fluid identifies which cells in the tissue to act upon? O The cell closest to the diffusion site. O The presence of a receptor located in the cytoplasm or nucleus specific to the hormone in cells. O The presence of a receptor embedded in the plasma membrane of target cells. O The presence of a channel protein embedded in the plasma membrane for the lipid-soluble hormone to diffuse through. Save for Later 80 F3 F4 F5 F6 8 F7 Attempts: 0 of 3 used F8 F9 Submit Answer F10arrow_forwardHormones are often synthesized and stored in an inactiveform within secretory vesicles. Secretion usually occurs onlywhen the hormone-producing cell is stimulated. Explain theadvantages that this process has over making the hormonemolecules as they are needed.arrow_forwardIf a hormone affects a target tissue through a membrane-bound receptorthat has a G protein associated with it, predict the consequences if agenetic disease causes the α subunit of the G protein to have a structurethat prevents it from binding to GTP.arrow_forward
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