To discuss:
The location of hormone receptors in the target cells and differences between hydrophilic and hydrophobic hormone receptor systems.
Introduction:
Hormones are chemical messengers secreted by the endocrine glands or neurosecretory cells into the extracellular fluids. The secreted hormones reach the target cells through the bloodstream, and they stimulate response of other tissues or cells. Hormones bind only to specific cells based on their corresponding receptors present on the cells. Hormones act through chemical signals. They regulate growth, development, blood pressure,
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ANATOMY AND PHYSIOLOGY THE UNITY OF FORM
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- Correctly order (from first to last) the steps involved in the Steroid mechanism of hormone action the harmone receptor complex is formed the steroid homorne diffuses into a cell's cytoplasm the hormone-receptor complex transloacates into the cell's nucleus transcription occurs followed by translation a newly formed protein initiates a cellular response the steroid harmone detaches from its protein carrierarrow_forwardWhich hormones require second messengersto activate a target cell; how second messengers work, especially cAMP, DAG, and IP3arrow_forwardEndocrinology Because they are relatively hydrophobic, peptide hormones can interact with both cytoplasmic and nuclear receptors, depending on the specific hormone. Rather than being stored in intracellular vesicles, catecholamine hormones are synthesized on demand and released immediately upon being synthesized. Although vasopressin is synthesized in the hypothalamus, it is released from the terminals of neurons located in the posterior pituitary.arrow_forward
- “Some hormones are produced as inactive and then get converted into active hormone” – justify this statement using an appropriate example.arrow_forwardEndocrine Ligand acting on intracellular receptor should be: O Hydrophilic O Hydrophobic O Amphipathic O Macromolecule What kinds of molecules may pass througharrow_forwardCyclic amp is involved in the mechanism of action that involves ____________ hormones. Group of answer choices Lipid-soluble Water-solublearrow_forward
- Examples of second messengers Steroid hormones Prostaglandins and leukotrienes NO and CO Epinephrine I, II, III, IV II, III, IV only I, II, III only I, III, IV onlyarrow_forwardWhat makes hormone binding to its receptor more like an allosteric regulator binding to an enzyme than a substrate binding to an enzyme is the way that hormone binding to its receptor works.arrow_forwardBe able describe peptide hormones in terms of their hydrophilicity or hydrophobicity, their ½ life, and the location of their receptors. (NOTE: TH does not fit into the general pattern).arrow_forward
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