Chapter 17.SE, Problem 27MP

Interpretation Introduction

Interpretation:

A mechanism for the reaction of epoxides with Grignard reagents to yield alcohols is to be proposed.

Concept introduction:

Carbon in Grignard reagents are negatively polarized and hence are nucleophilic. Thus it can attack the epoxide ring from the backside leading to the formation of a trans product.

To propose:

A mechanism for the reaction of epoxides with Grignard reagents to yield alcohols.