Chapter 18, Problem 21RQ

Summary Introduction

To explain:

The mechanism in which blocking the activity of the phosphodiesterase enzyme will affect the cell that responds to hormonal simulation by cAMP second messenger system.

Concept introduction:

Phosphodiesterase is an enzyme that is responsible for breaking the phosphodiester bond. There are many different types of phosphodiesterases. For example: RNases, DNases, sphingomyelin, restriction endonucleases and so on. They are important regulators for the signal transduction mediated by the secondary messenger molecules.