BIOLOGICAL SCIENCE (LSC-CUSTOM) VOL.1
BIOLOGICAL SCIENCE (LSC-CUSTOM) VOL.1
4th Edition
ISBN: 9781323462546
Author: Freeman
Publisher: PEARSON
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Chapter 18, Problem 5TYU
Summary Introduction

Introduction:

The lactose is the molecule that acts as an inhibitor of the repressor in the lac operon. The lac operon is active and acts efficiently when glucose is absent in the medium. It operates under the negative control, where inducer–repressor controls the activation of lac operon.

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E. coli has five genes that code for enzymes that make tryptophan. These genes are regulated by a single promoter and transcribed as one long gene. The presence of tryptophan shut down the production of tryptophan by the cell by binding to the repressor. This changes the repressors shape allowing it to bind to DNA operator, blocking RNA polymerase and cutting off the production of tryptophan. a. Describe what woud happen to the operon if some of the cells had a mutation on the repressor, not allowing it to bind with tryptophan. The repressor is described as an allosteric protein. What does this mean? b. Does the tryptophan model demonstrate an inducible or repressible operon? What is your evidence? *
E. coli has five genes that code for enzymes that make tryptophan. These genes are regulated by a single promoter and transcribed as one long gene. The presence of tryptophan shut down the production of tryptophan by the cell by binding to the repressor. This changes the repressors shape allowing it to bind to DNA operator, blocking RNA polymerase and cutting off the production of tryptophan. a. Describe what would happen to the operon if some of the cells had a mutation on the repressor, not allowing it to bind with tryptophan. The repressor is described as an allosteric protein. What does this mean? b. Does the tryptophan model demonstrate an inducible or repressible operon? What is your evidence?*
Which of the following best explains how the prokaryotic expression of a metabolic protein can be regulated when the protein is already present at a high concentration?   a.Repressor proteins can be activated and bind to regulatory sequences to block transcription.   b.Regulatory proteins can be inactivated to increase gene expression.   c.Transcription factors can bind to regulatory sequences to increase RNA polymerase binding.   d.Histone modification can prevent transcription of the gene.
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