Concept explainers
A.
To explain: Whether the mutation is dominant or recessive.
Concept introduction: Pedigree analysis is an approach that is used to study the inheritance of genes in humans. This approach is of great importance, as it can be used to construct a pedigree based on a family history and also to evaluate the given information in the pedigree by applying the laws of inheritance (law of segregation, law of dominance, and the law of independent assortment).
B.
To explain: Whether the mutation is carried on an autosome or sex chromosome.
Concept introduction: Pedigree analysis is an approach that is used to study the inheritance of genes in humans. This approach is of great importance, as it can be used to construct a pedigree based on a family history and also to evaluate the given information in the pedigree by applying the laws of inheritance (law of segregation, law of dominance, and the law of independent assortment).
C.
To explain: The number of haplotype blocks that is predicted to be found around the critical gene.
Concept introduction: Pedigree analysis is an approach that is used to study the inheritance of genes in humans. This approach is of great importance, as it can be used to construct a pedigree based on a family history and also to evaluate the given information in the pedigree by applying the laws of inheritance (law of segregation, law of dominance, and the law of independent assortment).
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