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Chapter 19, Problem 1CC

Ion regulation is a key feature of kidney function. What happens to the resting membrane potential of a neuron if extracellular K+ levels decrease? [p. 249]

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Summary Introduction

To determine: The condition of resting membrane potential when the extracellular potassium ion level decreases.

Introduction: Resting membrane potential (RMP) describes the voltage difference across the cell membrane when the cell is at rest. It is a result of distribution of charged particles.

Explanation of Solution

At rest, a typical neuron has a resting potential of -70 millivolts. The RMP of living cells is determined by the K+ concentration gradient and the cell’s resting permeability to Na+, K+, and Cl-.

An alteration in either K+ concentration gradient or ion permeability changes the membrane potential. For example, if the extracellular K+ levels decrease, the resting membrane potential will be more negative. This change in cell’s membrane potential is known as hyperpolarization.

Conclusion

The lower K+ levels in the extracellular space causes hyperpolarization of the resting membrane potential.

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Chapter 19 Solutions

Human Physiology: An Integrated Approach, Books a la Carte Edition and Modified Mastering A&P with Pearson eText - ValuePack Access Card (7th Edition)

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