Biology
11th Edition
ISBN: 9781259188138
Author: Peter H Raven, George B Johnson Professor, Kenneth A. Mason Dr. Ph.D., Jonathan Losos Dr., Susan Singer
Publisher: McGraw-Hill Education
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Chapter 19, Problem 5A
The genes that encode the morphogen gradients in Drosophila were all identified in mutant screens. A mutation that removes the gradient necessary for the A/P morphogen gradient would be expected to
a. affect the larvae but not the adult.
b. affect the adult but not the larvae.
c. be lethal and lead to an abnormal embryo.
d. produce replacement of one adult structure with another.
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Most organisms display a circadian rhythm, a cycling of biological processes that is roughly synchronized with day length. In Drosophila, pupae eclose (emerge as adults after metamorphosis) at dawn.
a)Using this knowledge how would screen for Drosophila mutants that have an impaired circadian rhythm?
b)In each case, how would you clone the genes you identified by mutation?
Which of the following statement(s) is/are true with regard to positional information in Drosophila?
A. Morphogens are a type of molecule that conveys positional information.
B. Morphogenetic gradients are established only in the oocyte, prior to fertilization.
C. Cell adhesion molecules also provide a way for a cell to obtain positional information.
What is true of the Progress Zone model?
a) the length of time a cell resides in the progress zone dictates its identity along the proximodistal axis
b) it is consistent with the outcome of removing the AER at successively later stages of limb development
c) once a cell leaves the progress zone, its identity is established along the proximodistal axis
d) cells of the progress zone are stimulated to divide by the AER
e) all of the above
You isolate a new mutant chicken strain in which limb outgrowth is severely curtailed. Limbdevelopment begins and the AER initially forms, but the AER then degenerates and subsequent development of the limb is aborted. Which of the following is a possible explanation for the AER phenotype?
a) the mutant gene may function cell autonomously in the AER
b) the mutant gene may function cell-nonautonomously in the limb bud mesenchyme
c) the mutant gene may interfere with the feedback loop between the mesenchyme and AER
d) all of the above
Chapter 19 Solutions
Biology
Ch. 19 - During development, cells become a. differentiated...Ch. 19 - Prob. 2UCh. 19 - Prob. 3UCh. 19 - Prob. 4UCh. 19 - Plant meristems a. are only present during...Ch. 19 - Prob. 6UCh. 19 - The process of nuclear reprogramming a. is a...Ch. 19 - What is the common theme in cell determination by...Ch. 19 - The process of reproductive cloning a. shows that...Ch. 19 - Prob. 3A
Ch. 19 - Prob. 4ACh. 19 - The genes that encode the morphogen gradients in...Ch. 19 - What would be the likely result of a mutation of...Ch. 19 - MADS-box, and Hox genes are a. found only in...Ch. 19 - The fate map for C. elegans (refer to figure 19.3)...Ch. 19 - Prob. 2SCh. 19 - You have generated a set of mutant embryonic mouse...Ch. 19 - Assume you have the factors in hand necessary to...
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