Based upon the mechanism of opposing concentration gradients of Bicoid and Caudal determine specification of the anterior-to-posterior axis in Drosophila melanogaster , and whether same mechanism work in a fly embryo that is larger or has different proportions per body segment. Also, determine precision of actual gradient and precision to set a nucleus/cell upon a lineage-specific path of maturation. Introduction: Research studies revealed that the cytoplasm of egg is not uniform as compared to other eggs. It comprises of ascents of positional information determining the cell density along the egg's anterior-posterior axis. In the syncytial blastoderm, nuclei in the frontal part of the cell are open to cytoplasmic determination factors usually not found in the posterior segment of the cell. These determination factors in differing amount with the nuclei specify cell fate.

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Based upon the mechanism of opposing concentration gradients of Bicoid and Caudal determine specification of the anterior-to-posterior axis in Drosophila melanogaster, and whether same mechanism work in a fly embryo that is larger or has different proportions per body segment. Also, determine precision of actual gradient and precision to set a nucleus/cell upon a lineage-specific path of maturation.

Introduction:

Research studies revealed that the cytoplasm of egg is not uniform as compared to other eggs. It comprises of ascents of positional information determining the cell density along the egg's anterior-posterior axis. In the syncytial blastoderm, nuclei in the frontal part of the cell are open to cytoplasmic determination factors usually not found in the posterior segment of the cell. These determination factors in differing amount with the nuclei specify cell fate.

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