Concept explainers
(a)
Interpretation: The Grignard reagent and
Concept introduction: One should follow the retrosynthetic pathway to find out the Grignard reagent and aldehyde (or ketone) needed to prepare an alcohol. This involves two steps. The first step is finding of carbon bonded to the
(b)
Interpretation: The Grignard reagent and aldehyde (or ketone) needed to prepare the given alcohol are to be predicted and the all possible routes are to be drawn.
Concept introduction: One should follow the retrosynthetic pathway to find out the Grignard reagent and aldehyde (or ketone) needed to prepare an alcohol. This involves two steps. The first step is finding of carbon bonded to the
(c)
Interpretation: The Grignard reagent and aldehyde (or ketone) needed to prepare the given alcohol are to be predicted and the all possible routes are to be drawn.
Concept introduction: One should follow the retrosynthetic pathway to find out the Grignard reagent and aldehyde (or ketone) needed to prepare an alcohol. This involves two steps. The first step is finding of carbon bonded to the
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ORGANIC CHEMISTRY-W/ACCESS
- Show how you might use the Williamson ether synthesis to prepare each ether. (a) (b)arrow_forwardWrite the appropriate reagent over each arrow.arrow_forwardDraw a stepwise mechanism for the following reaction, a key step in the synthesis of ticlopidine, a drug that inhibits platelet aggregation. Ticlopidine has been used to reduce the risk of stroke in patients who cannot tolerate aspirin.arrow_forward
- Draw a stepwise mechanism for the nitration of a benzene ring.arrow_forward(a) Give an acceptable name for compound A. (b) Draw the organic products formed when A is treated with each reagent: [1] H3O+; [2] −OH, H2O; [3] CH3CH2CH2MgBr (excess), then H2O; [4] LiAlH4, then H2O.arrow_forwardGive the IUPAC name for each aldehyde.arrow_forward
- Draw a stepwise mechanism for the sulfonation of an alkyl benzene such as A to form asubstituted benzenesulfonic acid B. Treatment of B with base forms a sodium salt C that canbe used as a synthetic detergent to clean away dirt.arrow_forwardDraw a stepwise mechanism for the following reaction, a key step in the synthesis of conivaptan (trade name Vaprisol), a drug used in the treatment of low sodium levels.arrow_forwardWhat ester and Grignard reagent are needed to synthesize each alcohol?arrow_forward
- What starting materials are needed to prepare each compound using a Heckreaction?arrow_forwardLinalool and lavandulol are two of the major components of lavender oil. (a) What organolithium reagent and carbonyl compound can be used to make each alcohol? (b) How might lavandulol be formed by reduction of a carbonyl compound? (c) Why can't linalool be prepared by a similar pathway?arrow_forwardDraw a stepwise mechanism for the following reaction that forms ether D. D can be converted to the antidepressant fluoxetine (trade name Prozac) in a single step.arrow_forward
- Organic ChemistryChemistryISBN:9781305580350Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. FootePublisher:Cengage Learning