Biology: Unity and Div. of Life (Looseleaf)
14th Edition
ISBN: 9781305251311
Author: STARR
Publisher: CENGAGE L
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Chapter 20, Problem 3DAA
Summary Introduction
To determine: Whether the given results support the hypothesis that the virus is adapting to host defenses.
Introduction: Human Immunodeficiency Virus (HIV) is a group of retroviruses that are sexually transmitted from one to another. It causes a disease that lead to life-threatening infections called AIDS. Here, the immune system fails or weakens due to viral infection and is accompanied with the development of many infections. Certain proteins called Human Leukocyte Antigens (HLA) are produced and displayed by our cells that act as a marker for the identification of unusual invaders in the body. Each unique marker is produced for the determination of self-cells versus the invaders by the immune system.
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This is a hypothetical scenario.
A recently emerged virus has been transmitting and mutating rapidly in humans throughout the world. If a vaccine that stops transmission of all current circulating variants of the virus in humans is utilized and herd immunity is achieved throughout the world, would this essentially stop 1) further transmission of the virus; 2) further mutation of the virus, respectively? Why/why not? Please answer the question succinctly and in bullet points!
When an antibody binds to the spike protein of SARS-CoV-2, it may block access of the spike protein to the ACE2 protein on human cells. This is one way an antibody can prevent the virus from attaching to and getting inside of human cells. But antibodies can do more than just block virus entry. Due to the symmetrical structure of the immunoglobulin molecule, it can bind to two antigen molecules simultaneously, like this:
As a result, antibodies can cross-link multiple viruses in a three-dimensional network. Using this diagram as a starting point, draw several additional viruses and antibodies to illustrate what a cross-linked antigen-antibody complex might look like.
Serum from individuals with high levels of antibody to SARS-CoV2 has been used to treat patients with severe COVID-19. What is ONE way (there are several) that passive immunization with the antibody to the virus could help these patients? HINT: think about what opsonization with antibody could do for the innate immune response.
Chapter 20 Solutions
Biology: Unity and Div. of Life (Looseleaf)
Ch. 20 - Prob. 1SQCh. 20 - Prob. 2SQCh. 20 - Prob. 3SQCh. 20 - Prob. 4SQCh. 20 - __________ do not reproduce sexually. a....Ch. 20 - Prob. 6SQCh. 20 - Adapting to Host Defenses Surface proteins called...Ch. 20 - Prob. 2DAACh. 20 - Prob. 3DAACh. 20 - Adapting to Host Defenses Surface proteins called...
Ch. 20 - Prob. 7SQCh. 20 - Bacteria that serve as decomposers are ___ . a....Ch. 20 - Prob. 9SQCh. 20 - Formation of a(n) ___ allows some soil bacteria to...Ch. 20 - Prob. 11SQCh. 20 - Prob. 12SQCh. 20 - Which of these diseases is caused by bacteria? a....Ch. 20 - Prob. 14SQCh. 20 - Prob. 15SQCh. 20 - If a cut or scrape becomes infected,...Ch. 20 - The adenoviruses that cause colds do not have a...Ch. 20 - Prob. 3CTCh. 20 - Prob. 4CT
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