MICROBIOLOGY W/ACCESS PKG >IP<
12th Edition
ISBN: 9781323592427
Author: Tortora
Publisher: PEARSON C
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Textbook Question
Chapter 20, Problem 4MCQ
An antimicrobial agent should meet all of the following criteria except
- a. selective toxicity.
- b. the production of hypersensitivities.
- c. a narrow spectrum of activity.
- d. no production of drug resistance.
- e. none of the above
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Students have asked these similar questions
An antimicrobial drug with a therapeutic index is a betterchoice than one with a therapeutic index.a. low, high
b. high, low
Choose the false statement below:
O Using three different classes of antimicrobials in combination greatly decreases the chance of
developing resistance because the drug resistance strategy for one is the same for others.
O Drug resistance to antimicrobials has proven to be extensive against chemotherapeutics as well
as other chemical antimicrobials.
O Collateral damage is a term that refers to the killing of normal body flora as well as pathogenic
bacteria when taking antimicrobials or antibiotics.
Which of the following statements concerning drug delivery system is INCORRECT?*
A.Drugs with good aqueous solubility are good for controlled release formulation.
B.The delay-released form is also called extended release form.
C.Absorption rate is higher in compressed tablets than that in capsules.
D.Drug core with polymer membrane coating belongs to diffusion sustained system.
E.Disintegration and dissolution can occur at the same time.
Chapter 20 Solutions
MICROBIOLOGY W/ACCESS PKG >IP<
Ch. 20 - DRAW IT Show where the following antibiotics work:...Ch. 20 - List and explain five criteria used to identify an...Ch. 20 - What similar problems are encountered with...Ch. 20 - Define drug resistance. How is it produced? What...Ch. 20 - List the advantages of using two chemotherapeutic...Ch. 20 - Why does a cell die from the following...Ch. 20 - How does each of the following inhibit...Ch. 20 - The OH is missing from carbon 39 in ddI. How does...Ch. 20 - Compare the method of action of the following...Ch. 20 - NAME IT This microorganism is not susceptible to...
Ch. 20 - Which of the following pairs is mismatched? a....Ch. 20 - Prob. 2MCQCh. 20 - Prob. 3MCQCh. 20 - An antimicrobial agent should meet all of the...Ch. 20 - The most selective antimicrobial activity would be...Ch. 20 - Prob. 6MCQCh. 20 - Which of the following will not affect eukaryotic...Ch. 20 - Cell membrane damage causes death because a. the...Ch. 20 - A drug that intercalates into DNA has the...Ch. 20 - Chloramphenicol binds to the 50S portion of a...Ch. 20 - Prob. 1ACh. 20 - Why is idoxuridine effective if host cells also...Ch. 20 - Some bacteria become resistant to tetracycline...Ch. 20 - The following data were obtained from a...Ch. 20 - Prob. 5ACh. 20 - The following results were obtained from a broth...Ch. 20 - Vancomycin-resistant Enterococcus faecalis was...Ch. 20 - Prob. 2CAECh. 20 - Prob. 3CAE
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- Potential negative side-effects of antibiotic use include all of the following except… A. Allergic Reaction B. Development of a superinfection C. Toxicity to an organ or tissue in your body D. Body developing immunity to the antibioticarrow_forwardThe list below choose all the concerns surrounding antimicrobial use. A. toxicity B. disruption of normal flora C. allergic reactions D. tolerance of effective dosearrow_forwardWhich clinical situation would be appropriate for treatment with a narrow-spectrum antimicrobial drug? Select one: a.prophylaxis against infection after a surgical procedure b.The treatment of strep throat caused by culture identified as Streptococcus pyogenes c.None of the Above d.the treatment of a polymicrobial mixed infection in the intestine e.Empiric therapy (based on educated guesswork) of pneumonia while waiting for culture resultsarrow_forward
- The clinical effectiveness of a drug majorly depends on: a. Clearance b. Potency c. Affinity to receptors d. Half-lifearrow_forwardChoose the combination of answers that most accurately completes the statement. Which statement is not an aim in the use of drugs in antimicrobial chemotherapy? The drug should a. have selective toxicity b. be active even in high dilutions c. be broken down and excreted rapidly d. be microbicidalarrow_forwardDifferentiate between the following and provide one example of each:a. antibiotics and antimicrobial drugs b. broad- and narrow-spectrum antimicrobialsarrow_forward
- List and explain in your own words the 5 mechanisms of antimicrobial drug resistancearrow_forwardPlease choose all the ADVANTAGES of protein-based drugs such as antibodies compare to small molecules from the following options. A. high selectivity B. Biocompatibility C. stable to metabolism D. oral bioavailability E. long half-life F. high activityarrow_forwardWhen two antimicrobial drugs are used at the same time, antagonistic effects can occur. Which of the following is NOT a possible antagonistic effect of combining two antimicrobial drugs? Increased elimination of one drug Increased activity of both drugs Increased toxicity Decreased therapeutic levels Decreased activity of both drugsarrow_forward
- List 10 characteristics of an ideal antimicrobial drug.arrow_forwardBroad-spectrum drugs target a wide variety of bacterial pathogens. Even when the broad-spectrum drug is capable of killing a target pathogen, it may not be the best treatment. Which statement best explains why a broad spectrum drug might be an undesirable treatment choice? Broad-spectrum antimicrobials are usually toxic to the host cells. Broad-spectrum antimicrobials only work if they are used shortly after the infection begins. Broad-spectrum antimicrobials may kill much of the normal microbiota. Broad-spectrum antimicrobials are not able to kill bacteria that are in their log phase of growth. Broad-spectrum antimicrobials may stimulate excess growth of the normal microbiota.arrow_forwardWhich of the following is NOT a property of an antimicrobial agent? a. Must have a known concentration over a period of time required to eliminate a pathogen b. all choices are correct c. must be selectively toxic d. Must have a favorable chemotherapeutic indexarrow_forward
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