Genetic Analysis: An Integrated Approach (2nd Edition)
Genetic Analysis: An Integrated Approach (2nd Edition)
2nd Edition
ISBN: 9780321948908
Author: Mark F. Sanders, John L. Bowman
Publisher: PEARSON
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Chapter 20, Problem 6P

What is the difference between a parasegment and segment in Drosophila development? Why do developmental biologists think of parasegments as the subdivisions that are produced during development of flies?

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You have identified a Drosophila gene that is expressed exclusively in the odd-numbered "stripes" in the cellular blastoderm. Assuming that this gene is not redundant, what would be the most likely phenotype cause by a loss-of-function mutation in this gene? an embryo missing odd numbered segments an adult fly with a second pair of wings instead of halteres an embryo with two anterior ends an embryo missing even-numbered segments an embryo missing larval segments 3-10
It seems that developmental genetics boils down to a complex network of gene regulation. Try to draw a structure of this network for Drosophila. How many genes do you think are necessary to complete the developmental network for the fruit fly? How many genes do you think are needed for a network to specify one segment? Do you think it is more difficult to identify genes that are involved in the beginning, middle, or end of this network? Suppose you were trying to identify all of the genes needed for development in a chicken. Knowing what you know about Drosophila development, would you first try to identify genes necessary for early development, or would you begin by identifying genes involved in cell differentiation?
What would be the most likely effect on development of puncturing the posterior end of a Drosophila egg, allowing a small amount of cytoplasm to leak out, and then injecting that cytoplasm into the anterior end of another egg?

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Genetic Analysis: An Integrated Approach (2nd Edition)

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