ORGANIC CHEMISTRY W/CONNECT & ALEKS
ORGANIC CHEMISTRY W/CONNECT & ALEKS
6th Edition
ISBN: 9781264683888
Author: SMITH
Publisher: MCG
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Chapter 21, Problem 44P

Devise a synthesis of valproic acid [ ( CH 3 CH 2 CH 2 ) 2 CHCO 2 H ] , a medicine used to treat epileptic seizures, using the malonic ester synthesis.

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Identify the best reagents to complete the following reaction.
Acetals are formed from the reaction of two alcohols with a carbonyl under acidic conditions. Acetal formation is faster with 1,2-ethanediol than with two methanol molecules. Choose the factor that explains the difference in reaction rates. A) The reaction with 1,2-ethanediol has a lower AH (enthalpy) of reaction. B) The reaction with 1,2-ethanediol has a higher AH (enthalpy) of reaction. C) The reaction with 1,2-ethanediol has a more favorable entropy of reaction.
provide appropriate reagents

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ORGANIC CHEMISTRY W/CONNECT & ALEKS

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