52-Year-Old Male with Multiple Sclerosis
Mr. Ayers was diagnosed with an aggressive form of multiple sclerosis 18 years ago. His illness has not responded to conventional treatments so he's been referred to your clinic for a clinical trial.
The doctor explains that his treatment will involve giving Mr. Ayers a drug that will release stem cells from his bone marrow so they can be collected from his blood. Then Mr. Ayers will be given (1) drugs that will destroy the blood-forming cells in his bone marrow, and (2), antibodies against his T lymphocytes. Finally, the stem cells that were collected from him will be used to repopulate his bone marrow.
The doctor says, “This treatment avoids problems, such as transplant rejection, that are associated with other kinds of transplants.”
4. NCLEX-STYLE You’re talking with Mr. Ayers about his course of treatment. Which of his statements indicates a need for further instruction?
a.“It's ironic that they’re giving me antibodies against my T cells, when I already attack my own tissues."
b.“I’m gonna ask the doc to not give me the stem cells after they destroy my bone marrow.
After all, the immune cells are what's hurting me!"
c.“My T cells are just brutal. Gotta get those bad boys under control!"
d.“I’m guessing the real trouble was something that happened to my T cells."
Want to see the full answer?
Check out a sample textbook solutionChapter 21 Solutions
HUMAN ANAT.+PHYSIO.(LL)-W/MASTER.+LAB
- What is Tumor necrosis factor-alpha (TNF-a)?arrow_forwardAlisa has asked her obstetrician to save and freeze her baby’s cord blood after delivery in case the child needs a future bone marrow transplant. What is in the baby’s cord blood that could be used to treat future disorders in the child?arrow_forwardQuinolones and fluroquinolones affect cell membrane integrity? True or false.arrow_forward
- The patient was a 13-month old child who, on the day of admission, seemed fine according to his mother except for a runny nose and a low-grade fever (which she treated with Tylenol). Later in the day, while riding in the car with his mother, he suddenly had a grand mal seizure with shaking of the arms and legs. The seizure lasted 2 minutes. She called an ambulance. The emergency medical technicians found him limp, unresponsive, and apparently post ictal (post seizure state). In the emergency room he had a second seizure. On physical examination, he had a temperature of 39.5 ° C, and a pulse of 160 BPM. He was noted to be lethargic, but his neck was supple. Except for a runny nose, the rest of his physical examination was normal. Blood and urine cultures were obtained to rule out sepsis, and the child was begun on IV ceftriaxone (rocephin). His vaccination record is incomplete, but his mother insists that he is up to date on all vaccines. The patient's mental status did not improve…arrow_forwardIt is determined that Susan will need to undergo chemotherapy and radiation to treat her cancer. How would this affect her choices of pharmacological treatments?arrow_forwardwhat is The genetic basis for chronic myelogenous leukemia ?arrow_forward
- Cellular disarray in the nerve cells of a person with schizophrenia means that the nerve cells appear: Question 5 options: a) Smaller b) Larger c) Organized d) Disorganizedarrow_forwardWhat do you mean by neuroplasma?arrow_forwardThe nurse is reviewing the orders for a newly admitted patient and sees an order for edrophonium (Tensilon). The nurse expects that this drug is ordered for which reason?a) To reduce symptoms and delay the onset of Alzheimer’s diseaseb) To treat the symptoms of myasthenia gravisc) To aid in the diagnosis of myasthenia gravisd) To reverse the effects of nondepolarizing neuromuscular blocking drugs after surgery.arrow_forward
- Mr. Martin is suffering from a condition known as ventricular tachycardia, in which his heart beats too quickly. Would an alpha-blocker or a beta-blocker help alleviate his problem? Why?arrow_forwardMarjory’s doctor prescribed Lodine, an anti-inflammatory, for her postoperative pain. Her nurse read the doctor’s order incorrectly, mistaking the “L” for an “I.” Instead of Lodine, she used Betadine, an iodine solution, to cleanse the wound. Marjory is allergic to iodine. What was the cause of this medication error?arrow_forwardA man with sickle-cell anemia is considering marriage. He is worried that his children might be born with sickle-cell anemia. What questions should he ask his fiancée?arrow_forward