EBK BIOLOGY
EBK BIOLOGY
11th Edition
ISBN: 8220102797352
Author: Raven
Publisher: YUZU
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Chapter 24, Problem 2U
Summary Introduction

Introduction:

Mutation is a process of alteration in nucleotide sequences of the genome of an organism. It occurs either naturally or artificially. Basically, it is the unpredictable change in the DNA sequence which is expressed slowly. Mutation is either useful or harmful. Itaffects a single gene in a base sequence or affect multiple genes in a nucleotide sequence.

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The original DNA base sequence is  5’-AGCGTTACCGT-3’; a mutation in the DNA strand results in the base sequence 5’-AGGCGTTACCGT-3’.  What can you conclude about the mutation?   A. It is a frameshift mutation.   B. It is a silent mutation.    C.  It is a deleterious mutation.   D. It may result in a single amino acid change in the protein being coded for by this base sequence.
What potential problems must be considered in creating a transgenic bacterium with the human insulin gene isolated from genomic DNA to produce insulin? a. The genetic code of bacteria is significantly different from the genetic code of humans. b. The bacterial cell will be unable to posttranslationally process the insulin peptide sequence. c. There is no way to get the bacterium to transcribe high levels of a human gene. d. Both a and b present problems.
What is the difference between orthologs and paralogs? a. Orthologs are homologous sequences; paralogs are analogous sequences. b. Orthologs are more similar than paralogs. c. Orthologs are in the same species; paralogs are in different species. d. Orthologs are in different species; paralogs are in the same species.
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