Concept explainers
Interpretation:
The relationship between insulin, GLUT4 obesity and type II diabetes is to be explained.
Concept introduction:
Type II form of diabetes mellitus is a
Glucose Transporter Type
Insulin is a peptide hormone secreted by the pancreas, while epinephrine (adrenaline) is a neurotransmitter and a hormone that is normally synthesized by the adrenal glands and some neurons.
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Chapter 24 Solutions
Bundle: Biochemistry, Loose-leaf Version, 9th + Owlv2,1 Term Printed Access Card
- REFLECT AND APPLY How do the control mechanisms in glycogen metabolism lead to amplification of response to a stimulus?arrow_forwardREFLECT AND APPLY Explain how phosphorylation is involved in the function of the sodiumpotassium ATPase.arrow_forwardREFLECT AND APPLY Avidin, a protein found in egg whites, binds to biotin so strongly that it inhibits enzymes that require biotin. What is the effect of avidin on glycogen formation? On gluconeogenesis? On the pentose phosphate pathway?arrow_forward
- REFLECT AND APPLY Outline the methods you would use to pro- duce human growth hormone (a substance used in the treatment of dwarfism) in bacteria.arrow_forwardREFLECT AND APPLY Explain how glycogen phosphorylase is controlled allosterically and by covalent modification.arrow_forwardREFLECT AND APPLY Explain the relationship between TFIID, TBP, and TAFs.arrow_forward
- REFLECT AND APPLLY High levels of glucose-6-phosphate inhibit glycolysis. If the concentration of glucose-6-phosphate decreases, activity is restored. Why?arrow_forwardREFLECT AND APPLLY What is the metabolic advantage of having both hexokinase and glucokinase to phosphorylate glucose?arrow_forwardREFLECT AND APPLY Argue logically that the urea cycle should not have evolved. Then, logically counter your argument.arrow_forward
- REFLECT AND APPLY Given the nature of the hormonal activation of lipases, what carbohydrate pathways would be activated or inhibited under the same conditions?arrow_forwardREFLECT AND APPLY How can the synthesis and breakdown of fructose-2,6-bisphosphate be controlled independently?arrow_forwardREFLECT AND APPLY A researcher claims to have discovered a variant form of glycogen. The variation is that it has very few branches (every 50 glucose residues or so) and that the branches are only three residues long. Is it likely that this discovery will be confirmed by later work?arrow_forward
- BiochemistryBiochemistryISBN:9781305961135Author:Mary K. Campbell, Shawn O. Farrell, Owen M. McDougalPublisher:Cengage Learning