HUMAN ANATOMY + PHYSIOLOGY + MAST AP
HUMAN ANATOMY + PHYSIOLOGY + MAST AP
11th Edition
ISBN: 9780136782056
Author: Marieb
Publisher: INTER PEAR
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Chapter 25, Problem 5CCS
Summary Introduction

Case summary:

Mr. Kyle Foulard just regained his health back after suffering from a crisis of acute diabetic. He is prescribed ACE that is angiotensin-converting enzyme inhibitor and a thiazide diuretic. He is given counseling on the significance of taking his medications on time and to follow his check-up routine on time. The following tests were obtained before he was discharged:

Urine: pH 6.9, negative for ketones and glucose; a 24-hour collection of urine showed 170 mg (milligram) albumin in urine per day; BP (blood pressure): 150/95, HR-75, and body temperature are 37.2°C.

Characters in the case:

Mr. Kyle Boulard, a man in his early 30s who is suffering from acute diabetes.

Adequate information:

Mr. Kyle is given thiazide diuretic and an ACE that is angiotensin-converting enzyme inhibitors after just recovering from acute diabetes crisis.

To determine:

The way in which ACE inhibitors reduces the blood pressure.

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A 3-month-old boy is brought to the emergency department because of a 20day history of lethargy. Physical examination shows no other abnormalities. The results of laboratory studies are shown: serum: Na+      165 mEa/L (N=139-146) Cl-         130 mEq/L (N=95-105) Osmolality   334 mOsmol/kg H2O (N=282-295) urine: specific gravity    1.001 osmolality            117 mOsmol/kg H2O (N>200) He is admitted to the hospital. His urine output is increased. His serum ADH (vasopressin) concentraion is 24 pg/mL (N=1-5); aldosterone and renin concentrations are within the reference ranges. The urine osmolality remains unchanges after administration of 1-deamino-B-arginine vasopressin. An MRI of the brain and pituitary gland shows no abnormalities. Ultrasonography shows normal kidneys. The most likely underlying cause of the findings in this patient is a defect in which of the following?a. angiotensin-converting enzyme b. aquaporin c. 11a-Hydroxylase d. renin e. vasopressin receptors
Please provide detail understanding and hand written solution
Blood Analysis Glu = 5.0; Na = 145; K = 2.8. Back to patient's chart Glucose Sodium Potassium Calcium Iron Thomas (male) Age: 28 Triage Data complained of abrupt polydipsia (excessive thirst) and polyuria (excessive urine volume, 15 L per day) T3 (triiodothyronine) T4 (thyroxine) 3.9 135 3.5 2.15 Thomas (male) Age: 28 5 0.24 62 Low DII Other Long Description Ca = 2.50 Fe = 27 T3 = 0.33 T4 = 99 glucose urinalysis = 0.0 mmol/L Click here for Report Form Normal
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