In the structure of human insulin, to indicate where in each chain the molecule is cleaved by trypsin and chymotrypsin. Concept introduction: Partial hydrolysis of a peptide can be carried out using enzymes which are specific in their action. The enzyme trypsin catalyses the hydrolysis of peptides only at the carboxyl side of the basic amino acids arginine and lysine. The enzyme chymotrypsin cleaves only at the carboxyl side of the aryl substituted amino acids phenylalanine, tyrosin and tryptophan. To indicate: In the structure of human insulin, where in each chain the molecule is cleaved by trypsin and chymotrypsin.

Question

Want to see the full answer?

Answer 1

Question

Chapter 26.SE, Problem 55AP

Interpretation Introduction

Interpretation:

In the structure of human insulin, to indicate where in each chain the molecule is cleaved by trypsin and chymotrypsin.

Concept introduction:

Partial hydrolysis of a peptide can be carried out using enzymes which are specific in their action. The enzyme trypsin catalyses the hydrolysis of peptides only at the carboxyl side of the basic amino acids arginine and lysine. The enzyme chymotrypsin cleaves only at the carboxyl side of the aryl substituted amino acids phenylalanine, tyrosin and tryptophan.

To indicate:

In the structure of human insulin, where in each chain the molecule is cleaved by trypsin and chymotrypsin.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Students have asked these similar questions

If H218O is used in the hydrolysis reaction catalyzed by lysozyme, which ring will contain the label, NAM or NAG?

Treatment of a new protein with dansyl chloride reveals two (2) dansyl-labelled derivatives of amino acids, alanine and methionine. What can you deduce about the structure of the proteinfrom these results?

The imidazole ring on Histamine has a pKa of 6.5. What is the %ionization of this group at pH 8.2?

Answer 2

Question

Chapter 26.SE, Problem 55AP

Interpretation Introduction

Interpretation:

In the structure of human insulin, to indicate where in each chain the molecule is cleaved by trypsin and chymotrypsin.

Concept introduction:

Partial hydrolysis of a peptide can be carried out using enzymes which are specific in their action. The enzyme trypsin catalyses the hydrolysis of peptides only at the carboxyl side of the basic amino acids arginine and lysine. The enzyme chymotrypsin cleaves only at the carboxyl side of the aryl substituted amino acids phenylalanine, tyrosin and tryptophan.

To indicate:

In the structure of human insulin, where in each chain the molecule is cleaved by trypsin and chymotrypsin.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Answer 3

Question

Chapter 26.SE, Problem 55AP

Interpretation Introduction

Interpretation:

In the structure of human insulin, to indicate where in each chain the molecule is cleaved by trypsin and chymotrypsin.

Concept introduction:

Partial hydrolysis of a peptide can be carried out using enzymes which are specific in their action. The enzyme trypsin catalyses the hydrolysis of peptides only at the carboxyl side of the basic amino acids arginine and lysine. The enzyme chymotrypsin cleaves only at the carboxyl side of the aryl substituted amino acids phenylalanine, tyrosin and tryptophan.

To indicate:

In the structure of human insulin, where in each chain the molecule is cleaved by trypsin and chymotrypsin.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Answer 4

Question

Chapter 26.SE, Problem 55AP

Interpretation Introduction

Interpretation:

In the structure of human insulin, to indicate where in each chain the molecule is cleaved by trypsin and chymotrypsin.

Concept introduction:

Partial hydrolysis of a peptide can be carried out using enzymes which are specific in their action. The enzyme trypsin catalyses the hydrolysis of peptides only at the carboxyl side of the basic amino acids arginine and lysine. The enzyme chymotrypsin cleaves only at the carboxyl side of the aryl substituted amino acids phenylalanine, tyrosin and tryptophan.

To indicate:

In the structure of human insulin, where in each chain the molecule is cleaved by trypsin and chymotrypsin.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Answer 5

Chapter 26.SE, Problem 55AP

Interpretation Introduction

Interpretation:

In the structure of human insulin, to indicate where in each chain the molecule is cleaved by trypsin and chymotrypsin.

Concept introduction:

Partial hydrolysis of a peptide can be carried out using enzymes which are specific in their action. The enzyme trypsin catalyses the hydrolysis of peptides only at the carboxyl side of the basic amino acids arginine and lysine. The enzyme chymotrypsin cleaves only at the carboxyl side of the aryl substituted amino acids phenylalanine, tyrosin and tryptophan.

To indicate:

In the structure of human insulin, where in each chain the molecule is cleaved by trypsin and chymotrypsin.

Answer 6

Chapter 26.SE, Problem 55AP

Interpretation Introduction

Interpretation:

In the structure of human insulin, to indicate where in each chain the molecule is cleaved by trypsin and chymotrypsin.

Concept introduction:

Partial hydrolysis of a peptide can be carried out using enzymes which are specific in their action. The enzyme trypsin catalyses the hydrolysis of peptides only at the carboxyl side of the basic amino acids arginine and lysine. The enzyme chymotrypsin cleaves only at the carboxyl side of the aryl substituted amino acids phenylalanine, tyrosin and tryptophan.

To indicate:

In the structure of human insulin, where in each chain the molecule is cleaved by trypsin and chymotrypsin.

Answer 7

Chapter 26.SE, Problem 55AP

Interpretation Introduction

Interpretation:

In the structure of human insulin, to indicate where in each chain the molecule is cleaved by trypsin and chymotrypsin.

Concept introduction:

Partial hydrolysis of a peptide can be carried out using enzymes which are specific in their action. The enzyme trypsin catalyses the hydrolysis of peptides only at the carboxyl side of the basic amino acids arginine and lysine. The enzyme chymotrypsin cleaves only at the carboxyl side of the aryl substituted amino acids phenylalanine, tyrosin and tryptophan.

To indicate:

In the structure of human insulin, where in each chain the molecule is cleaved by trypsin and chymotrypsin.

Answer 8

Expert Solution & Answer

Answer 9

Expert Solution & Answer

Answer 10

Want to see the full answer?

Check out a sample textbook solution

See solution

Answer 11

Ch. 26.1 - How many of the -amino acids shown in Table 26-1...Ch. 26.1 - Prob. 2P Ch. 26.1 - Prob. 3P Ch. 26.2 - Hemoglobin has pI=6.8. Does hemoglobin have a net...Ch. 26.3 - Show how you could prepare the following -amino...Ch. 26.3 - What alkyl halides would you use to prepare the...Ch. 26.3 - Prob. 7P Ch. 26.4 - There are six isomeric tripeptides that contain...Ch. 26.4 - Draw the structure of M-P-V-G, and indicate its...Ch. 26.5 - Prob. 10P

Solution Summary: The author explains how trypsin catalyzes the hydrolysis of peptides only at the carboxyl side of the basic amino acids arginine and lysine, while chymotry

Concept explainers

Videos

Want to see the full answer?

Chapter 26 Solutions