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Chapter 27, Problem 4CCS

23-Year-Old Female with Menstrual Irregularity

Jasmine Herrera, 23, has been referred to the endocrinology clinic. She is very overweight, with obvious acne and facial hair. She complains of irregular menstrual cycles. “My husband and I want to use the rhythm method," she says, “but I don’t have any rhythm!”

Chapter 27, Problem 4CCS, 23-Year-Old Female with Menstrual Irregularity Jasmine Herrera, 23, has been referred to the

4. Jasmine thinks that having so many follicles means she is extremely fertile. Is her assumption correct?

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A 26-year-old female complained of severe, dull, aching pain, and cramping in the lower abdomen. There were no other physical findings. A laparoscopy revealed the presence of ectopic endometrial tissue on the uterine wall and ovaries. Danazol (a synthetic androgen and inhibitor of gonadotropins), 600 mg/day, was prescribed for up to nine months to inhibit ovulation, suppress the growth of the abnormal endometrial tissue, and achieve appreciable symptomatic relief, with a 30% possibility of conception after withdrawal of the therapy. Top of Form What is the rationale for using danazol, a gonadotropin inhibitor?
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