23-Year-Old Female with Menstrual Irregularity
Jasmine Herrera, 23, has been referred to the endocrinology clinic. She is very overweight, with obvious acne and facial hair. She complains of irregular menstrual cycles. “My husband and I want to use the rhythm method," she says, “but I don’t have any rhythm!”
5. Jasmine’s blood tests reveal very high levels of androgens. She is diagnosed with polycystic ovary syndrome (PCOS). In this syndrome, the woman develops high levels of androgens and many vesicular follicles, but has reduced fertility because few follicles are ovulated and the timing of their release is unpredictable. Part of the profile of PCOS is that LH levels are high. How would this lead to androgen excess, and what clinical evidence of androgen excess does Jasmine have?
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Chapter 27 Solutions
HUMAN A&P E-TEXT ACCESS CODE
- Mr. Morningstar has no history of serious medical conditions. Although he tested negative for RPR, HBsAg and HIV, he confided that he used to have sex with both men and women in the Bar he owned in Los Angeles a year ago. According to him, that was before his relationship with Ms. Decker. He also mentioned that before they travelled here in the Philippines two weeks ago, he shared a few bottles of beer and Kansas-style barbecue with his brother named Amenadiel in Midtown Missouri. He also offered you (the interviewer) a sachet of crystal clear methamphetamine. Will you accept Mr. Morningstar as a Donor for Patient Chloe Decker? What are the following parameters that you will consider in order to accept or defer Mr. Morningstar as a Donor for Patient Chole Decker? Justify your answers.arrow_forwardMr. Morningstar has no history of serious medical conditions. Although he tested negative for RPR, HBsAg and HIV, he confided that he used to have sex with both men and women in the Bar he owned in Los Angeles a year ago. According to him, that was before his relationship with Ms. Decker. He also mentioned that before they travelled here in the Philippines two weeks ago, he shared a few bottles of beer and Kansas-style barbecue with his brother named Amenadiel in Midtown Missouri. Will you accept Mr. Morningstar as a Donor for Patient Chloe Decker? What are the following parameters that you will consider in order to accept or defer Mr. Morningstar as a Donor for Patient Chole Decker? Justify your answers.arrow_forwardA 26-year-old female complained of severe, dull, aching pain, and cramping in the lower abdomen. There were no other physical findings. A laparoscopy revealed the presence of ectopic endometrial tissue on the uterine wall and ovaries. Danazol (a synthetic androgen and inhibitor of gonadotropins), 600 mg/day, was prescribed for up to nine months to inhibit ovulation, suppress the growth of the abnormal endometrial tissue, and achieve appreciable symptomatic relief, with a 30% possibility of conception after withdrawal of the therapy. Top of Form What is the rationale for using danazol, a gonadotropin inhibitor?arrow_forward
- A 26-year-old female complained of severe, dull, aching pain, and cramping in the lower abdomen. There were no other physical findings. A laparoscopy revealed the presence of ectopic endometrial tissue on the uterine wall and ovaries. Danazol (a synthetic androgen and inhibitor of gonadotropins), 600 mg/day, was prescribed for up to nine months to inhibit ovulation, suppress the growth of the abnormal endometrial tissue, and achieve appreciable symptomatic relief, with a 30% possibility of conception after withdrawal of the therapy. Top of Form Why do you think oral contraceptives could also be used as a treatment?arrow_forwardA 26-year-old female complained of severe, dull, aching pain, and cramping in the lower abdomen. There were no other physical findings. A laparoscopy revealed the presence of ectopic endometrial tissue on the uterine wall and ovaries. Danazol (a synthetic androgen and inhibitor of gonadotropins), 600 mg/day, was prescribed for up to nine months to inhibit ovulation, suppress the growth of the abnormal endometrial tissue, and achieve appreciable symptomatic relief, with a 30% possibility of conception after withdrawal of the therapy. Compare the hormonal controls of the male reproductive cycle with the hormonal controls of the female reproductive cycle. How are they the same? How are they different?arrow_forwardMrs. Zexy Lucero, 30 years old, G1P0, 6 weeks by LMP presents at the lying in clinic for prenatal check-up. History revealed a Type 1 diabetes since 14 years of age, history of diabetic nephropathy and proliferative retinopathy and is bothered about the effects on her baby. Which of the following statements about diabetes in pregnancy needs further instructions? (SELECT ALL THAT APPLIES) a. Diabetes ketoacidosis is a common complication during the first trimester. b. Glycosylated hemoglobin levels are poor predictors of the risk of congenital malformations c. Proteinuria over 300 mg/dL is associated with increased risk of preeclampsia. d. The risk of fetal chromosomal abnormalities is increased.arrow_forward
- Description A-45-year-old woman presents complaining of fatigue, 30 pounds of weight gain despite dieting, constipation, and menorrhagia. On physical examination, the thyroid is not palpable: the skin is cool, dry, and rough: the heart sounds are quiet; and the pulse rate is 50 bpm. The rectal and pelvic examinations show no abnormalities, and the stool is negative for occult blood. The clinical findings suggest hypothyroidism. Questions A. What other features of the history should be elicited? What other findings should be sought on physical examination? B. What is the pathogenesis of this patient's symptoms? C. What laboratory tests should be ordered, and what results should be anticipated? D. What are the possible causes of this patient's condition? Which is most likely? E. What other conditions may be associated with this disorder?arrow_forwardI need quick responsearrow_forwardA young woman has been experiencing unusually heavy menstrual bleeding for several years. She follows a strict vegan diet (no animal foods). She is at risk for what disorder, and why?arrow_forward
- Mr. J, 29, and Ms. S, 30, have been together for five years. A year ago, they decided they wanted to have a baby, and they stopped using birth control. At first, they did not pay attention to the timing of their sexual activity in relation to Ms. S menstrual cycle, but after six months passed without Ms. S becoming pregnant, they decided to try to maximize their efforts. They knew that in order for a woman to become pregnant, the man’s sperm must encounter the woman’s egg, which is typically released once a month through a process called ovulation. They also had heard that for the average woman, ovulation occurs around day 14 of the menstrual cycle. To maximize their chances of conception, they tried to have sexual intercourse on day 14 of Ms. S menstrual cycle each month. After several months of trying this method, Ms. S is still not pregnant. She is concerned that she may not be ovulating on a regular basis because her menstrual cycles are irregular and often longer than the average…arrow_forwardDescription of symptoms Find out what disease this patient has • Absent menstruation • Hirsutism Acne Depression • • Obesity Facial hair (hirsutism)arrow_forwardPatient Profile: Stanley is a college student taking up engineering in one of the university in Metro Manila. He lives alone in the dormitory and his province is Bicol. He was diagnosed of Syphilis. History: -Stanley is a 19-year-old male who presents to the STD clinic because he’s - had a sore on his penis for one week. -Last sexual exposure was three weeks prior, without a condom. -No history of recent travel. -Predominantly female partners (five in the last six months), and occasional male partners (three in the 1-2 years). -Last HIV antibody test (two months prior) was negative. Reports three children with two different women. All children were in the province taking care of by his parents. He is single and always on the go to mingle. Physical Exam: -No oral, perianal, or extra-genital lesions. -Genital exam shows an uncircumcised penis with a lesion on the ventral side near the frenulum. Lesion is red, indurated, clean-based, and non-tender. -Two enlarged tender right…arrow_forward