Concept explainers
Agglutination is a reaction, it occurred between particle-bound antigen and antibody and that results in a visible clump of the particles. Agglutination tests are widely used in various clinical diagnostics because, they are quick to perform, highly specific, inexpensive, reasonably sensitive, and cost-effective. Also, agglutination tests may not need expensive equipment. In addition, agglutination test can be performed in test tubes or microtiter plates. These characteristics make agglutination tests to use in a wide range of clinical applications (for example, to identify blood group antigens, pathogens, and their products). Agglutination test can be distinguished into direct and passive agglutination.
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Brock Biology of Microorganisms (14th Edition)
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