GENETICS:FROM GENES TO GENOMES-ACCESS
6th Edition
ISBN: 9781260472981
Author: HARTWELL
Publisher: MCG
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Chapter 5, Problem 25P
In Drosophila, three autosomal genes have the following map:
| a. | Provide the data, in terms of the expected number of flies in the following females are crossed to a b c / a b c males. Assume 1000 flies are counted and that no interference exists in this region.  |
| b. | If the cross was reversed, such that a b c / a b c males are crossed to a b c / a b c females, how many flies would you expect in the same phenotypic classes? |
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in the image
Q. Construct a linkage map showing the correct order of these genes and estimate the distances between them.
a. In Drosophila, crosses between F1 heterozygotes ofthe form A b / a B always yield the same ratio ofphenotypes in the F2 progeny regardless of the distance between the two genes (assuming completedominance for both autosomal genes). What is thisratio? Would this also be the case if the F1 heterozygotes were A B / a b? (Hint: Remember that inDrosophila, recombination does not take placeduring spermatogenesis.)b. If you intercrossed F1 heterozygotes of the formA b / a B in mice, the phenotypic ratio among the F2progeny would vary with the map distance betweenthe two genes. Is there a simple way to estimate themap distance based on the frequencies of the F2phenotypes, assuming rates of recombination areequal in males and females? Could you estimatemap distances in the same way if the mouse F1heterozygotes were A B / a b?
Chapter 5 Solutions
GENETICS:FROM GENES TO GENOMES-ACCESS
Ch. 5 - Choose the phrase from the right column that best...Ch. 5 - a. A Drosophila male from a true-breeding stock...Ch. 5 - Prob. 3PCh. 5 - The Punnett square in Fig. 5.4 shows how Mendels...Ch. 5 - In mice, the dominant allele Gs of the X-linked...Ch. 5 - In Drosophila, males from a true-breeding stock...Ch. 5 - If the a and b loci are 20 m.u. apart in humans...Ch. 5 - CCDD and ccdd individuals were crossed to each...Ch. 5 - In mice, the autosomal locus coding for the...Ch. 5 - In a particular human family, John and his mother...
Ch. 5 - Albino rabbits lacking pigment are homozygous for...Ch. 5 - In corn, the allele A allows the deposition of...Ch. 5 - If the a and b loci are 40 cM apart and an AA BB...Ch. 5 - Write the number of different kinds of phenotypes,...Ch. 5 - A DNA variant has been found linked to a rare...Ch. 5 - Figure 5.7a shows chromosomes during prophase of...Ch. 5 - Figure 5.7b shows bivalents in mouse primary...Ch. 5 - Cinnabar eyes cn and reduced bristles rd are...Ch. 5 - In Drosophila, the autosomal recessive dp allele...Ch. 5 - From a series of two-point crosses, the following...Ch. 5 - Map distances were determined for four different...Ch. 5 - In the tubular flowers of foxgloves, wild-type...Ch. 5 - In Drosophila, the recessive allele mb of one gene...Ch. 5 - A snapdragon with pink petals, black anthers, and...Ch. 5 - In Drosophila, three autosomal genes have the...Ch. 5 - Drosophila females heterozygous for each of three...Ch. 5 - Male Drosophila expressing the autosomal recessive...Ch. 5 - a. In Drosophila, crosses between F1 heterozygotes...Ch. 5 - A true-breeding strain of Virginia tobacco has...Ch. 5 - Prob. 30PCh. 5 - The following list of four Drosophila mutations...Ch. 5 - Do the data that Mendel obtained fit his...Ch. 5 - Two genes control color in corn snakes as follows:...Ch. 5 - A mouse from a true-breeding population with...Ch. 5 - Neurospora of genotype a c are crossed with...Ch. 5 - A cross was performed between one haploid strain...Ch. 5 - Prob. 40PCh. 5 - Prob. 41PCh. 5 - Indicate the percentage of tetrads that would have...Ch. 5 - Prob. 43PCh. 5 - This problem leads you through the derivation of a...Ch. 5 - a. In ordered tetrad analysis, what is the maximum...Ch. 5 - Prob. 46PCh. 5 - A single yeast cell placed on a solid agar will...Ch. 5 - Figure 5.29 shows mitotic recombination leading to...Ch. 5 - A diploid strain of yeast has a wild-type...Ch. 5 - In Drosophila, the yellow y gene is near the...Ch. 5 - Neurofibromas are tumors of the skin that can...Ch. 5 - Two important methods for understanding the...
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