EBK FUNDAMENTALS OF ANATOMY & PHYSIOLOG
11th Edition
ISBN: 9780134477312
Author: Bartholomew
Publisher: YUZU
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Chapter 5, Problem 26RQ
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Based on the FRAP data in Q4.3 above, what can you infer about the cell motility (movement) breast cancer cells and non‑cancerous breast cells?
Profilin I belongs to a family of small actin binding proteins that are thought to work at the leading
edge of actin in migrating cells. Notably, expression of Profilin I is down-regulated in breast and
various other cancer cells.
A
1.2
29
Breast Cancer Cells
Fluorescence
recovery (A.U.)
1.0
0.8-
0.6-
0.4-
Control
Extra Profilin added
0.2-
5
10 15
20 25
30
Time (s)
Based on the data above, hypothesize why cancer cells might downregulate Profilin 1 compared to
noncancerous cells?
The VPS mutant below disrupts Golgi-to-endosome trafficking in the lysosomal pathway compared
to wild-type.
vacuole
Wild-type
endosomes
Golgi
ER
The statement above is:
Correct
Incorrect
VPS mutant
Chapter 5 Solutions
EBK FUNDAMENTALS OF ANATOMY & PHYSIOLOG
Chapter 5, Problem 1CPChapter 5, Problem 2CPChapter 5, Problem 3CPChapter 5, Problem 4CPChapter 5, Problem 5CPChapter 5, Problem 6CPChapter 5, Problem 7CPChapter 5, Problem 8CPChapter 5, Problem 9CPChapter 5, Problem 10CP
Chapter 5, Problem 11CPChapter 5, Problem 12CPChapter 5, Problem 13CPChapter 5, Problem 14CPChapter 5, Problem 15CPChapter 5, Problem 16CPChapter 5, Problem 17CPChapter 5, Problem 18CPChapter 5, Problem 19CPChapter 5, Problem 20CPChapter 5, Problem 21CPChapter 5, Problem 22CPChapter 5, Problem 23CPChapter 5, Problem 24CPChapter 5, Problem 25CPChapter 5, Problem 26CPChapter 5, Problem 27CPChapter 5, Problem 28CPChapter 5, Problem 29CPChapter 5, Problem 30CPChapter 5, Problem 31CPChapter 5, Problem 32CPChapter 5, Problem 1RQChapter 5, Problem 2RQChapter 5, Problem 3RQChapter 5, Problem 4RQChapter 5, Problem 5RQChapter 5, Problem 6RQChapter 5, Problem 7RQChapter 5, Problem 8RQChapter 5, Problem 9RQChapter 5, Problem 10RQChapter 5, Problem 11RQChapter 5, Problem 12RQChapter 5, Problem 13RQChapter 5, Problem 14RQChapter 5, Problem 15RQChapter 5, Problem 16RQChapter 5, Problem 17RQChapter 5, Problem 18RQChapter 5, Problem 19RQChapter 5, Problem 20RQChapter 5, Problem 21RQChapter 5, Problem 22RQChapter 5, Problem 23RQChapter 5, Problem 24RQChapter 5, Problem 25RQChapter 5, Problem 26RQChapter 5, Problem 27RQChapter 5, Problem 28RQChapter 5, Problem 29RQChapter 5, Problem 30RQChapter 5, Problem 31RQChapter 5, Problem 1CCChapter 5, Problem 2CC
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