Genetics: A Conceptual Approach
Genetics: A Conceptual Approach
6th Edition
ISBN: 9781319050962
Author: Benjamin A. Pierce
Publisher: W. H. Freeman
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Chapter 5.1, Problem 16AQP
Summary Introduction

To determine:

The penetrance of the PITXI mutation in the family in which club foot was inherited as an autosomal dominant trait with incomplete penetrance.

Introduction:

Clubfoot is a congenital, dominant, autosomal trait that can be inherited over generations. It is a foot abnormality in which the baby’s feet are twisted out of shape during childhood, but usually present at birth (congenital). This congenital disease can be mild or severe. The cause of clubfoot may be genetic or non-genetic.

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