PRESCOTT'S MICROBILOGY
11th Edition
ISBN: 9781264075515
Author: WILLEY
Publisher: MCG
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Chapter 6, Problem 3AL
Consider the separate stages of an animal virus life cycle. Assemble a short list of structures and processes that are unique to the virus and would make good drug targets for an antiviral agent. Explain your rationale for each choice.
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Chapter 6 Solutions
PRESCOTT'S MICROBILOGY
Ch. 6.2 - MICRO INQUIRY Which capsids are icosahedral? Which...Ch. 6.2 - Prob. 2MICh. 6.2 - MICRO INQUIRY Why is T4 said to have binal...Ch. 6.2 - Retrieve, Infer, Apply 1. How are viruses similar...Ch. 6.2 - Retrieve, Infer, Apply 2. What is the difference...Ch. 6.2 - Retrieve, Infer, Apply 3. Compare the structure of...Ch. 6.2 - Prob. 4CCCh. 6.2 - Retrieve, Infer, Apply 5. All four nucleic acid...Ch. 6.3 - MICRO INQUIRY Which of these mechanisms involves...Ch. 6.3 - MICRO INQUIRY Why do the empty capsids remain...
Ch. 6.3 - Explain why the receptors that viruses have...Ch. 6.3 - What probably plays the most important role in...Ch. 6.3 - How do you think the complexity of the viral...Ch. 6.3 - In general, DNA viruses can be much more dependent...Ch. 6.3 - Consider the origin of viral envelopes and suggest...Ch. 6.3 - Why are the proteins involved in virion assembly...Ch. 6.4 - Why is a lysogen considered a new or different...Ch. 6.4 - Define the terms lysogeny, temperate phage,...Ch. 6.4 - What advantages might a phage gain by being...Ch. 6.4 - Describe lysogenic conversion and its...Ch. 6.4 - How does a latent infection differ from a chronic...Ch. 6.4 - What is a cytocidal infection? What is a...Ch. 6.4 - Define the following terms: tumor, neoplasia,...Ch. 6.4 - Distinguish the mechanism by which dsDNA viruses...Ch. 6.5 - Prob. 1MICh. 6.5 - Prob. 1CCCh. 6.5 - Given that viruses must be cultivated to make...Ch. 6.7 - What are viroids and why are they of great...Ch. 6.7 - How does a viroid differ from a virus? From a...Ch. 6.7 - What is a prion? In what way does a prion differ...Ch. 6.7 - Prob. 4CCCh. 6 - Prob. 1RCCh. 6 - Prob. 2RCCh. 6 - Many classification schemes are used to identify...Ch. 6 - The origin and evolution of viruses is...Ch. 6 - Consider the separate stages of an animal virus...
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- Please provide a general definition of a virus. Viruses can cause other issues, known as cytopathic effects. Provide 3 effects and discuss why that effect can be very damaging to the host.arrow_forwardSome retroviruses that have a wide host range have been developed for use in treatment of diseases or syndromes. These viruses do not result in a productive infection because they lack critical genes for viral replication, but they do carry DNA sequences that allow them to be packaged into infectious particles. Once in the host cell the viral DNA is released and integrates into the cell's genome. The advantage to this strategy is that the delivery of the DNA is very efficient. What is one possible problem of using a virus that can integrate into the human nuclear genome? Multiple Choice The virus carries genes that will interfere with host cell activities. The viral DNA sequences could still cause a disease. Since the viral DNA sequences no longer contain essential genes for viral replication the host cell may not be able to replicate either. The integration could disrupt an essential gene or genes.arrow_forwardList three differences between the structure of HIV and the virus that causes influenza. For one of these differences, explain how the STRUCTURE is key to the FUNCTION of the virus.arrow_forward
- Explain the difference between a virus and a retrovirus. Give an example of both. Thank youarrow_forwardViruses: a. Describe the structure and composition of viruses. What are three reasons that they are different from cellular organisms? b. Describe what a lysogenic bacteriophage is and how it is different from a lytic bacteriophage. c. Describe what is similar and different about the lifecycle of a non-enveloped DNA animal virus compared to an enveloped animal retrovirus.arrow_forwarddiscuss the benefits and limitations of using a retroviral system or an adenovirus for the delivery of a therapeutic gene.arrow_forward
- Explain how a drug that blocks DNA recombination would affect the life cycle of HIV. Be as specific as possible.arrow_forwardAnswer the following regarding the varicella-zoster virus: a) the biology of the virus ( type: DNA/RNA type: single or double stranded) b) how it replicates c) life cycle of the virus (binding, fusion, reverse transcription, integration, replication, and assembly)arrow_forwarddiscuss the similarities and differences between animal and bacterial virus multiplication. (Words/concepts to include in your answer: attachment, adsorption, penetration, uncoating, synthesis, assembly, persistence, lysogeny, latency, release)arrow_forward
- Briefly describe the events leading to the synthesis of viral proteins. Begin with the genome; assume this is a negative single-stranded RNA virus (-SSRNA).arrow_forwardDefine the terms "latency" and "lysogeny" as they refer to viruses. Describe at least TWO ways these two processes are similar. Describe at least TWO ways these two processes are different.arrow_forwardCoronaviruses have a positive-sense single stranded RNA genome. a.) What is the genome replication strategy of this category of viruses? b.) How do you think this feature affects the stability of the viral genome? (hint use figure below) Mutation rates in different types of viruses. Estimates obtained for viruses belonging to the major indicated groups are shown as a function of genome size. This reveals an effect of genetic material (RNA/DNA) and genome size on viral mutation rates.arrow_forward
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