Concept explainers
(a)
Interpretation:
Among the given curves, the curve that represents the given perturbation is to be identified.
Concept introduction:
Proteins are the
(b)
Interpretation:
Among the given curves, the curve that represents the given perturbation is to be identified.
Concept introduction:
Proteins are the biomolecules which are composed of the long chain of amino acid residues. The protein which contains oxygen and is present in the red blood cells in the body is known as hemoglobin. It contains iron as well.
(c)
Interpretation:
Among the given curves, the curve that represents the given perturbation is to be identified.
Concept introduction:
Proteins are the biomolecules which are composed of the long chain of amino acid residues. The protein which contains oxygen and is present in the red blood cells in the body is known as hemoglobin. It contains iron as well.
(d)
Interpretation:
Among the given curves, the curve that represents the given perturbation is to be identified.
Concept introduction:
Proteins are the biomolecules which are composed of the long chain of amino acid residues. The protein which contains oxygen and is present in the red blood cells in the body is known as hemoglobin. It contains iron as well.
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Check out a sample textbook solution- Some terms will not be used. The prosthetic group of hemoglobin and myoglobin is The organic ring component of heme is Under normal conditions, the central atom of heme is In the central iron atom is displaced 0.4 Å out of the plane of the porphyrin ring system. The central atom has bonds: to nitrogen atoms in the porphyrin, one to a residue, and one to oxygen. Answer Bank Fe3+ three heme serine deoxyhemoglobin four Fe2+ oxyhemoglobin рoгphyrin histidine six cysteinearrow_forwardBe able to describe the hemoglobin binding curve and why it is S shaped. Why is the shape important for loading and off-loading Oxygen? What is subunit cooperativity?arrow_forward. Oxygen binding by the hemocyanin of the shrimp Callianassa has been measured. Using the following data, prepare a Hill plot and determine (a) Pso, (b) h (the Hill coefficient), and (c) the minimum number of oxygen binding sites on the protein molecule. Poz (mm Hg) Yoz Po, (mm Hg) Yo2 1.1 0.003 136.7 0.557 7.7 0.019 166.8 0.673 10.7 0.035 203.2 0.734 31.7 0.084 262.2 0.794 71.9 0.190 327.0 0.834 100.5 0.329 452.0 0.875 123.3 0.487 736.7 0.913arrow_forward
- calculate the actual free energy of hydrolysis of ATP, delta Gp in the erythrocytes of a new species. The standard free-energy of hydrolysis of ATP is also -30.5kJ/mol in this species, but the concentrations in this specie's erythrocytes are 0.00775 mM ATP, 0.00027 mM ADP and 0.00418 mM Pi. Assume the pH is 7.0 and the body temperature of this species is 43.0oC. Calculate your answer as kJ/mol to two decimal places.arrow_forwardLabel the following equation. The parentheses represent the choices for each label (A-D). A. (Carbon Dioxide, Glucose, Water, Oxygen) B. (Carbon Dioxide, Glucose, Water, Oxygen) C. (Carbon Dioxide, Glucose, Water, Oxygen) D. (Carbon Dioxide, Glucose, Water, Oxygen)arrow_forwardAnimals breathe in oxygen. What is this atmospheric oxygen used for in the human body? (Give the name of the process where atmospheric oxygen is used and explain what happens to the atmospheric oxygen molecule.)arrow_forward
- You happen to pass a bar. Distracted by your entrance into the bar, one of the humans inadvertently drank a beverage containing 80 ml methanol. Unfortunately, no medical personnel are on the station, and you do not have access to sickbay. Assume that methanol and ethanol have densities of 0.79 g/ml, and that the alcohols distribute themselves rapidly over the total volume of 73 liters of body fluids of your host. A quick check of the biochemistry textbook that you always carry with you when traversing the promenade reveals that the Km of alcohol dehydrogenase for ethanol is 1 mM and for methanol the Km is 10 mM, and reminds you that alcohol dehydrogenase converts ethanol into acetaldehyde (which can then be converted to acetyl-CoA). Alcohol dehydrogenase also converts methanol into formaldehyde, which is quite toxic to humans. Ingesting 80 ml of methanol will permanently harm the human unless you intervene.b. Someone has a single 600 ml bottle of Romulan ale (52% ethanol), which he is…arrow_forwardLabel the following equation. The parentheses represent the choices for each label (A-D). A. (Water, glucose, Carbon dioxide, Oxygen). B. (Water, glucose, Carbon dioxide, Oxygen) C. (Water, glucose, Carbon dioxide, Oxygen) D. (Water, glucose, Carbon dioxide, Oxygen)arrow_forward"Hemoglobin can be in either an oxy- or deoxy- state at a given pH. Given the appropriate pKa values, calculate fraction protonated at a given pH" How would I do this?arrow_forward
- In addition to O, binding, changes in other chemical conditions can result in hemoglobin changes. pH is one of those factors. It can be understood by reaction #1. Red blood cells have the enzyme Carbonic Anhydrase which catalyzes reaction #2. Using the two reactions explain how pH contributes to the transfer of O2 from the lungs to the tissues. H-Hb* + O2 Hb-O2 + H* Reaction #1 CO2(aq) + H2O= H* + HCO3 Reaction #2arrow_forwardNeed help A patient with sickle cell anemia is given oxygen to decrease the sickling of the cells. What would be the reaction (if any) if the patient was given glucose instead of oxygen and why?arrow_forwardBohr for me, not for thee. Does myoglobin exhibit a Bohr effect? Why or why not?arrow_forward
- Human Physiology: From Cells to Systems (MindTap ...BiologyISBN:9781285866932Author:Lauralee SherwoodPublisher:Cengage Learning