EBK CONCEPTS OF GENETICS
EBK CONCEPTS OF GENETICS
12th Edition
ISBN: 9780134818979
Author: Killian
Publisher: YUZU
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Chapter 7, Problem 2PDQ

Review the Chapter Concepts list on p. 151. These all center around sex determination or the expression of genes encoded on sex chromosomes. Write a short essay that discusses sex chromosomes as they contrast with autosomes.

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With regard to the numbers of sex chromosomes, explain whydosage compensation is necessary
Mitotic nondisjunction can occur, particularly in tumor cells. Assume a single nondisjunction event involving the X chromosome occurs in a cell undergoing mitosis in a human female. First, consider the daughter cell with the smaller number of chromosomes: How many total chromosomes will this cell have?  How many X chromosomes will this cell have?    Next, consider the daughter cell with the larger number of chromosomes: How many total chromosomes will this cell have?  How many X chromosomes will this cell have?
Why is aneuploidy of the sex chromosomes less debilitating than aneuploidy of even the smallest autosomes? (Note: multiple responses are correct, please choose the best answer(s)) Select one or more: Only one X chromosome is required at any given time.  Additional X chromosomes (as in females) are inactivated in most cells except for gametes Dosage compensation requires that all excess chromosomes (i.e. 2 or more) are activated at all times during the cell cycle The Y chromosome carries a number of critical genes involved in spermatogenesis and sex development.  Therefore, having two copies of the Y chromosome results in the overproduction of sperm and increased fertility The Y chromosome carries a number of critical genes required for spermatogenesis and sex development, but very few other genes.  Therefore, having two copies of the Y chromosome has minimal impact on the balance of gene expression

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EBK CONCEPTS OF GENETICS

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