HUMAN PHYSIOLOGY(LL)(FD)
15th Edition
ISBN: 9781260704327
Author: Fox
Publisher: MCGRAW-HILL CUSTOM PUBLISHING
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Chapter 7, Problem 37RA
Summary Introduction
To review:
The time taken by the membrane potential to go from resting membrane potential to zero mV (millivolts).
Introduction:
Membrane potential can be described as the difference of electric potential that exists between the interior and the exterior environment of a cell. The value ranges from -40 mV to -80 mV. The reason behind the generation of action potential is the rapid movement of sodium ions inside the cell which is then followed by a efflux of potassium ions at a slower rate.
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1. What ions are flowing (and in which direction) both during the rising phase
and the falling phase of the action potential?
2. What are the values of both the 'y' (vertical) axis and the 'x' (horizontal) axis.
3. If extracellular levels of K+ rose (a condition called hyperkalemia), how would
that affect the resting membrane potential?
3
The presence of an electrical gradient is responsible for both the resting membrane potential and the action potential in the neuron.a. In this case who is responsible for maintaining the electric gradient to produce a potential for the resting membrane?b. Explain what is meant by an electrical gradient in the context of a cell (neuron)!
Describe the contribution of each of the following to the establishment and maintenance of membrane potential:
Part A
Na+K+ Pump
Passive movement of K+ across the membrane
Passive movement of Na+ across the membrane
Part B
Resting membrane potential is approximately -70mV. Explain what resting membrane potential is and what -70mV refers to.
Chapter 7 Solutions
HUMAN PHYSIOLOGY(LL)(FD)
Ch. 7 - Draw a neuron, label its parts, and describe the...Ch. 7 - Distinguish between sensory neurons, motor...Ch. 7 - Describe the structure of the neurilemma, and...Ch. 7 - Explain how myelin sheaths are formed in the CNS....Ch. 7 - Explain what is meant by the blood-brain barrier....Ch. 7 - Define the terms depolarization and...Ch. 7 - Prob. 4bCPCh. 7 - Describe how gating of Na+andK+ in the axon...Ch. 7 - Prob. 5aCPCh. 7 - Prob. 5bCP
Ch. 7 - Prob. 6aCPCh. 7 - Describe the location of neurotransmitters within...Ch. 7 - Describe the sequence of events by which action...Ch. 7 - Explain how chemically regulated channels differ...Ch. 7 - Prob. 8CPCh. 7 - Prob. 9aCPCh. 7 - Prob. 9bCPCh. 7 - Prob. 10CPCh. 7 - Prob. 11CPCh. 7 - Prob. 12aCPCh. 7 - Prob. 12bCPCh. 7 - Prob. 13aCPCh. 7 - Prob. 13bCPCh. 7 - Prob. 14aCPCh. 7 - Describe the mechanism of action of glycine and...Ch. 7 - Give examples of endogenous opioid polypeptides,...Ch. 7 - Prob. 15bCPCh. 7 - Prob. 16CPCh. 7 - Prob. 17aCPCh. 7 - Prob. 17bCPCh. 7 - Prob. 17cCPCh. 7 - Prob. 1RACh. 7 - Prob. 2RACh. 7 - Prob. 3RACh. 7 - Prob. 4RACh. 7 - Repolarization of an axon during an action...Ch. 7 - As the strength of a depolarizing stimulus to an...Ch. 7 - Prob. 7RACh. 7 - Which of these is not a characteristic of synaptic...Ch. 7 - Prob. 9RACh. 7 - Prob. 10RACh. 7 - Prob. 11RACh. 7 - Prob. 12RACh. 7 - Prob. 13RACh. 7 - Prob. 14RACh. 7 - Prob. 15RACh. 7 - Prob. 16RACh. 7 - Prob. 17RACh. 7 - Which of these may be produced by the action of...Ch. 7 - Prob. 19RACh. 7 - In a step-by-step manner, explain how the...Ch. 7 - Prob. 21RACh. 7 - Prob. 22RACh. 7 - Prob. 23RACh. 7 - Prob. 24RACh. 7 - Once an EPSP is produced in a dendrite, how does...Ch. 7 - Prob. 26RACh. 7 - List the endogenous opioids in the brain and...Ch. 7 - Explain what is meant by long-term potentiation...Ch. 7 - Prob. 29RACh. 7 - Prob. 30RACh. 7 - Prob. 31RACh. 7 - Prob. 32RACh. 7 - Prob. 33RACh. 7 - Explain the nature of the endocannabinoids....Ch. 7 - Prob. 35RACh. 7 - Prob. 36RACh. 7 - Prob. 37RACh. 7 - Prob. 38RACh. 7 - Prob. 39RACh. 7 - Use the figure below (from figure 7.34) to answer...
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Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- If a cell with the following ion concentrations had a resting membrane potential of -40mV which of the following can you conclude? Extracellular: Cl- = 110 mM, Na+ = 145 mM, K+ = 5mM. Intracellular Cl- = 20 mM, Na+ = 10 mM, K+ = 140mM a) At rest it is only permeable to potassium b) At rest it has some permeability to more than one of these ions c) At rest it is only permeable to chloride d) Rest it is not permeable to sodiumarrow_forwardRefer to the figure below to explain the mediation of action potentials by neurons using sodium and potassium channels at each of the six timepoints indicated.arrow_forwardCompare the resting membrane potential of a neuron with the potassium and sodium equilibrium potentials. Explain how this comparison relates to the relative permeabilities of the resting plasma membrane to these two ions.arrow_forward
- Draw details of the repolarization phase of an action potential from the following descriptions of the sequences of AfterHyperPolarization (AHP) and AfterDePolarization (ADP) sequences. Make the distinct phases clear and noticeable (5 % each) A complex AHP consisting of a first component AHP, an ADP, and a second component AHP before repolarization to resting membrane potential a first fast AHP component, followed by a slower AHP, followed by a fast ADP, and a second late AHP component before repolarization to restarrow_forwarddescribe what the resting membrane potential of a cell is. What is the resting membrane potential of neurons (give units)? What are the two factors that generate the resting membrane potential? Think of scenarios that change the factors that generate the resting membrane potential and how that would change the overall resting membrane potential.arrow_forwardDescribe the contribution of each of the following to the establishment and maintenance of membrane potential: Part A Na+K+ Pump Passive movement of K+ across the membrane Passive movement of Na+ across the membranearrow_forward
- Jose measures membrane potential in two neighboring cells. He notices that when the membrane potential changes in one cell, the membrane potential of the neighboring cell changes in a similar manner. For example, if one cell hyperpolarizes, the neighboring cell also hyperpolarizes. He concludes the cells are electrically coupled. Which of the following is the most likely to cause the electrical coupling? a.) The electrical coupling is most probably due to integrins that connect the two cells. b.) The electrical coupling is most probably due to tight junctions that connect the two cells. c.) The electrical coupling is most probably due to desmosomes that connect the two cells. d.) The electrical coupling is most probably due to gap junctions that connect the two cells.arrow_forwardWhat is the equilibrium membrane potential due to Na+ ions if the extracellular concentration of Na+ ions is 154 mM and the intracellular concentration of Na+ ions is 23 mM at 20 ∘C ?arrow_forwardThe normal concentrations for intracellular and extracellular potassium in a neuron are [K+]in = 150 mM and [K+]out = 5 mM, respectively. Due to an electrolyte imbalance, a patient has the following intracellular and extracellular concentrations of potassium: [K+]in = 140 mM and [K+]out =2 mM. Using the Nernst equation (Chapter 4), calculate the equilibrium potential for potassium in the cells with normal K+ distributions and of the diseased patient. Refer back to Question #1. Will it be easier or more difficult to generate an action potential in the diseased neuron as compared to the normal neuron? Why?arrow_forward
- Please explain what the resting membrane potential is and its value. Make sure you include all structures involved in the creation and maintenance of the resting membrane potential. Explanation addressing the question above Membrane potential is the difference in electric potential between the interior and the exterior of a biological cell. With respect to the exterior of the cell, typical values of membrane potential range from -40 mV to -80 mV. The membrane potential has two basic functions as a battery and transmitting signals between different parts of a cell. In non-excitable cells, the membrane potential is held at a relatively stable value, called the resting potential. The resting membrane potential of a neuron is about -70 mV. At rest, there are relatively more sodium ions outside the neuron and more potassium ions inside that neuron. It is determined by concentration gradients of ions across the membrane and by membrane permeability to each type of ion. Structure and…arrow_forwardExplain the following; If a drug partly blocks a membrane’s potassium channels, how does it affect the action potential? Suppose the threshold of a neuron were the same as the neuron’s resting potential. What would happen? At what frequency would the cell produce action potentials?arrow_forwardIn an essay describe in detail types of potentials seen in neurons and give examples?arrow_forward
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