To discuss:
The source of parathyroid hormone and multiple mechanisms by which it corrects hypocalcemia.
Introduction:
Mineralization is a process (crystallization) that deposits phosphate, calcium, and other ions (from blood plasma) in the tissues of the bone as hydroxyapatite. This process is initiated by the osteoblast by laying collagen fibers on the surface of the osteon. These fibers are coated with minerals that make the matrix hard. Only if the concentration of the products (of above minerals) in the plasma reaches the critical value (solubility product), the hydroxyapatite is formed. Sometimes, calcification is repressed by some inhibitors found in the tissue. This inhibitor is deactivated by osteoblast, and it enables the precipitation of the salt in the matrix of the bone. The initially formed crystals perform like a “seed of crystals” that attract more phosphate and calcium from the plasma.
Want to see the full answer?
Check out a sample textbook solutionChapter 7 Solutions
Anatomy & Physiology: The Unity of Form and Function
- REGULATION OF THYROID STIMULATING HORMONEarrow_forwardList of clinical symptoms and an explanation of at least one of the major symptoms of Congential Adrenal Hyperplasia disease with respect to its biochemistry.arrow_forwardAdrenal steroids that regulate glucose metabolism are collectively called _____.arrow_forward
- How the Congential Adrenal Hyperplasia disease changes the normal pathway, highlighting the enzyme/protein that is defective.arrow_forward“Among all the endocrine glands there is one, which is most susceptible towards hyper or hypofunction” – elucidate this statement with a detailed description on the abnormalities.arrow_forwardhormonal regulation of metabolism of the exercising skeletal muscle - -insulin -androgens -cortisol -GH -thyroid hormones each of itarrow_forward
- Biology: The Unity and Diversity of Life (MindTap...BiologyISBN:9781305073951Author:Cecie Starr, Ralph Taggart, Christine Evers, Lisa StarrPublisher:Cengage LearningHuman Physiology: From Cells to Systems (MindTap ...BiologyISBN:9781285866932Author:Lauralee SherwoodPublisher:Cengage LearningUnderstanding Health Insurance: A Guide to Billin...Health & NutritionISBN:9781337679480Author:GREENPublisher:Cengage