Chapter 8, Problem 1Q

Summary Introduction

Introduction:

Priming is regarded as the first contact of a T or B cell with its particular antigen, which further leads to differentiation into effector B or T cells (cytotoxic, antibody, cytokine). The priming of immature T cells needs dendritic cell antigen presentation. The priming of the immature CD8 T cell produces cytotoxic T cells possessing the tendency of directly eradicating the pathogen-infected cells.

Answer to Problem 1Q

Correct answer:

The correct answer is option (a) it occurs in primary lymphoid organs.

Explanation of Solution

Explanation for the correct answer:

Option (a) it occurs in primary lymphoid organs. The process of priming of T cells does not take place in primary lymphoid organs. Primary lymphoid organs are the locations where the lymphocytes are produced and gets developed. So, the correct answer is option (a).

Explanation for the incorrect answer:

Option (b) it transforms naïve T cells into differentiated effector T cells. In T-cell priming, the transformation of naïve T cells into differentiated T cells takes place. Thus, the mentioned statement is not relevant to the given question. So, this is an incorrect option.

Option (c) It is the first stage of a primary adaptive immune response. T cell priming is an initial stage of a primary adaptive immune response. Thus, the mentioned statement is not relevant to the given question. So, this is an incorrect option.

Option (d) It requires interaction between the naïve T cells and antigen presenting cells. The priming of immature T cells needs dendritic cell antigen presentation. Thus, the mentioned statement is not relevant to the given question. So, this is an incorrect option.

Option (e) It takes place in many locations, but not limited to lymph nodes, Peyer's patches, and the tonsils. T cell priming takes place when the T cell comes in contact with the antigen, and it can take place in various locations. Thus, the mentioned statement is not relevant to the given question. So, this is an incorrect option.

Conclusion

All of the following are true in reference to T-cell priming except that it takes place in primary lymphoid organs. Hence, the correct answer is option (a) it occurs in primary lymphoid organs.