Concept explainers
a.
To determine: The number of doublings that will take place before the normal cells cease to divide and its consistency with the telomerase hypothesis.
Introduction: Cancer can be of different types depending upon the type of cells, organ affected, and stage. The spreading of cancer to other places in the body is called metastasis. Cancer can be defined as the uncontrolled growth and proliferation of cells that compete with the normal cells for nutrition, space and eventually cause the death of normal cells
b.
To determine: The number of doubling that can take place in telomerase plus cell lines after which they fail to divide.
Introduction: The loss of telomere DNA restrains the ability of human cells to proliferate. The telomeres are present at the end of the chromosomes and contain repetitive DNA sequences. These sequences are shortened with time, and the telomeres length reduces, which takes place with aging.
Want to see the full answer?
Check out a sample textbook solutionChapter 8 Solutions
The Living World
- Human Anatomy & Physiology (11th Edition)BiologyISBN:9780134580999Author:Elaine N. Marieb, Katja N. HoehnPublisher:PEARSONBiology 2eBiologyISBN:9781947172517Author:Matthew Douglas, Jung Choi, Mary Ann ClarkPublisher:OpenStaxAnatomy & PhysiologyBiologyISBN:9781259398629Author:McKinley, Michael P., O'loughlin, Valerie Dean, Bidle, Theresa StouterPublisher:Mcgraw Hill Education,
- Molecular Biology of the Cell (Sixth Edition)BiologyISBN:9780815344322Author:Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter WalterPublisher:W. W. Norton & CompanyLaboratory Manual For Human Anatomy & PhysiologyBiologyISBN:9781260159363Author:Martin, Terry R., Prentice-craver, CynthiaPublisher:McGraw-Hill Publishing Co.Inquiry Into Life (16th Edition)BiologyISBN:9781260231700Author:Sylvia S. Mader, Michael WindelspechtPublisher:McGraw Hill Education